Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li+8 more
wiley +1 more source
Identification of Campylobacter species by southern hybridization of genomic DNA using an oligonucleotide probe for 16S rRNA genes [PDF]
Paul J. Romaniuk, T J Trust
openalex +1 more source
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi+8 more
wiley +1 more source
A method for high‐throughput production of sequence‐verified DNA libraries and strain collections
The low costs of array‐synthesized oligonucleotide libraries are empowering rapid advances in quantitative and synthetic biology. However, high synthesis error rates, uneven representation, and lack of access to individual oligonucleotides limit the true
Justin D Smith+15 more
doaj +1 more source
Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences. [PDF]
Dembska A+3 more
europepmc +1 more source
Modified oligonucleotides as alternatives to the synthesis of mixed probes for the screening of cDNA libraries. [PDF]
T. Huynh‐Dinh+4 more
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DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding+5 more
wiley +1 more source
Light‐Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing
Light harvesting (LH) in plants inspires researchers to develop artificial LH nanomaterials. Here, LH nanomaterials based on organic dyes are reviewed, considering fundamental challenges on aggregation‐caused quenching, excitation energy transfer, and exciton migration length.
Andrey S. Klymchenko+2 more
wiley +1 more source
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi+4 more
wiley +1 more source
Probing activated sludge with oligonucleotides specific for proteobacteria: inadequacy of culture-dependent methods for describing microbial community structure [PDF]
Michael Wagner+3 more
openalex +1 more source