Results 251 to 260 of about 148,528 (314)

Dual probe ligation in situ hybridization with rolling-circle amplification for high-plex spatial transcriptomics. [PDF]

open access: yesBiochem Biophys Rep
Maguire SE   +14 more
europepmc   +1 more source

A TtAgo‐Driven Autocatalytic Circuit with Thermal‐Enhanced Kinetics for One‐Pot Nucleic Acid Detection

open access: yesAdvanced Science, EarlyView.
This study proposes a universal catalytic DNA circuits termed TACTIC (Thermus thermophilus protein‐driven autocatalytic circuit) for one‐pot detection of DNA and RNA in multiple clinical samples. Integrated with machine learning, TACTIC accurately profile the distinct expression of four extracellular vesicle‐derived miRNAs across different samples and ...
Zuowei Xie   +12 more
wiley   +1 more source

Differential stability and dynamics of DNA-based and RNA-based coacervates affect non-enzymatic RNA chemistry. [PDF]

open access: yesNat Commun
Nakashima KK   +11 more
europepmc   +1 more source

Advancing Efficient Error Reduction in DNA Data Storage Systems with Deep Learning‐Based Denoising Models

open access: yesAdvanced Intelligent Discovery, EarlyView.
Deep learning‐based denoising models are applied to DNA data storage systems to enhance error reduction and data fidelity. By integrating DnCNN with DNA sequence encoding methods, the study demonstrates significant improvements in image quality and correction of substitution errors, revealing a promising path toward robust and efficient DNA‐based ...
Seongjun Seo   +5 more
wiley   +1 more source

Yeast pre-rRNA is processed at the A' site. [PDF]

open access: yesMicroPubl Biol
Dutca LM, Freed EF, Baserga SJ.
europepmc   +1 more source

A denaturation-free protocol for in situ visualization of short nuclear DNA sequences using padlock probes with rolling-circle amplification. [PDF]

open access: yesPLoS One
Ikebuchi R   +8 more
europepmc   +1 more source

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