Results 261 to 270 of about 414,656 (346)

Pol θ-mediated end-joining uses microhomologies containing mismatches. [PDF]

Nat Commun
Li Y, Dang NK, He W, Returan M, Carvajal-Maldonado D, Guerin AT, Xu H, Liu B, Wood RD.   +8 more
europepmc   +1 more source

Vasopressin and oxytocin mRNA regulation in the rat assessed by hybridization with synthetic oligonucleotides.

, 1983
Joseph A. Majzoub, Anina N. Rich, J van Boom, Joel F. Habener   +3 more
openalex   +1 more source

Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle‐Mediated Angiogenesis and the NF‐κB–PCLAF Signaling Axis

Advanced Science, EarlyView.
Clathrin Light Chain B (CLTB) drives hepatocellular carcinoma progression through dual pathways: intracellularly, it activates the NF‐κB–PCLAF axis to enhance small extracellular vesicle (sEV) uptake and tumor proliferation; extracellularly, CLTB‐enriched sEVs bind SH3KBP1 to inhibit its degradation, inducing angiogenesis and vascular leakage ...
Xiaoke Sun, Junchen Guo, Ning Zhao, Guanghua Cui, Yun Bai, Meijuan Ding, Yi Xu, Yu Yang   +7 more
wiley   +1 more source

Increasing Oligonucleotide Sequencing Information and Throughput with Ion Mobility Spectrometry-Mass Spectrometry. [PDF]

J Am Soc Mass Spectrom
Ryan JP, Slysz GW, Rye P, Stow SM, Dodds JN, Sausen J, Baker ES.   +6 more
europepmc   +1 more source

Self‐Propelled Magnetic Micromotor‐Functionalized DNA Tile System for Autonomous Capture of Circulating Tumor Cells in Clinical Diagnostics

Advanced Science, EarlyView.
The magnetic micromotor‐functionalized DNA‐array hunter (MMDA hunter), integrating autonomous propulsion and precision‐partitioned functionalities, utilizes DNA array programmability and 5'‐3' directional control to achieve spatially partitioned module arrangement.
Qiumei Pu, Liangqing Lu, Yanghong Zhao, Dongxia Li, Mengli Yao, Qionglin Zhou, Xinxin Xiao, Yuzhong Jia, Xuan Zhao, Xiangde Lai, Qian Chen, Yuxiang Ji, Bin Qiao, Hua Pei, Yanan Peng, Qiang Wu   +15 more
wiley   +1 more source

Towards One-Step and Universal Synthesis of Hypermodified Uracil Nucleosides: acp³U and cmnm⁵U

Mejdr E, Heinickel L, Carell T, Mejdr I.
europepmc   +1 more source

Phosphoglycerate dehydrogenase stabilizes protein kinase C delta type mRNA to promote hepatocellular carcinoma progression. [PDF]

Signal Transduct Target Ther
Cheng B, Peng P, Chen S, Liu R, Li X, Wang K, Ma J, Wang K, Tang N, Huang A.   +9 more
europepmc   +1 more source

Dimer‐Specific FokT‐seq Reveals DNA‐Binding Dimerization and Novel Genomic Targets of TDP‐43

Advanced Science, EarlyView.
Loss of TDP‐43 dimerization is implicated in ALS, yet its mechanistic role remains elusive. This study introduces FokT, a novel system that restores TDP‐43 dimerization to map its DNA targets via FokT‐seq. The findings uncover key binding sites and offer a versatile tool for exploring dimer‐dependent transcriptional regulation.
Mingming Yang, Qi Wang, Ruolan Yan, Xiaochuan Wang, Jianlan Gu   +4 more
wiley   +1 more source

ASOs reduce SARS-CoV-2 viral titers in Syrian golden hamsters. [PDF]

Mol Ther Nucleic Acids
Rossi JJ.
europepmc   +1 more source

CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1

Advanced Science, EarlyView.
CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang, Xin Yang, Lei Xing, Hang Chen, Fuming Xie, Bin Wang, Bowen Shi, Yan Yang, Junxia Chen   +8 more
wiley   +1 more source