Results 261 to 270 of about 571,586 (377)
Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu+17 more
wiley +1 more source
Robust Photocleavable Linkers for DNA Synthesis: Enabling Visible Light-Triggered Antisense Oligonucleotide Release in 3D DNA Nanocages. [PDF]
Leung HM+7 more
europepmc +1 more source
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan+16 more
wiley +1 more source
Effect of chemical modification on the exon-skipping activity of heteroduplex oligonucleotides. [PDF]
Shimo T+8 more
europepmc +1 more source
Primer‐Disk‐Enabled DNA Data Storage System with Index and Record‐Many‐Read‐Many Features
A primer‐disk‐enabled DNA data storage system is introduced, which allows for append‐recording of DNA files on demand, retrieval via inkjet printed QR code, and multiple ramdom read of DNA information via solid‐phase PCR. The hiearchical system with index and record‐many‐read‐many features paves the way for the practical use of DNA data storage ...
Jiaxiang Ma+5 more
wiley +1 more source
Engineering antisense oligonucleotides for targeted mRNA degradation through lysosomal trafficking. [PDF]
Kashyap D, Milne TA, Booth MJ.
europepmc +1 more source
The chemistry of oligonucleotide phosphotriesters and phosphoramidates
Robert L. Letsinger
openalex +2 more sources
Designing chemically modified oligonucleotides for targeted gene silencing.
G. Deleavey, M. Damha
semanticscholar +1 more source