Results 321 to 330 of about 449,240 (358)

Optochemical control over mRNA translation by photocaged phosphorodiamidate morpholino oligonucleotides in vivo. [PDF]

Nat Commun
Tarbashevich K, Ghosh A, Das A, Kuilya D, Sharma SN, Sinha S, Raz E.   +6 more
europepmc   +1 more source

Advances in the recombinase polymerase amplification platform for urogenital schistosomiasis diagnosis (ShDraI-RPA) towards implementation at the point-of-care. [PDF]

Sci Rep
Mesquita SG, Donnelly O, Archer J, Lugli EB, Webster B.   +4 more
europepmc   +1 more source

Metabolic Stability and Targeted Delivery of Oligonucleotides: Advancing RNA Therapeutics Beyond The Liver. [PDF]

J Med Chem
Anand P, Zhang Y, Patil S, Kaur K.
europepmc   +1 more source

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Oligonucleotide lipoplexes: the influence of oligonucleotide composition on complexation

Biochimica et Biophysica Acta (BBA) - General Subjects, 2001
Despite extensive investigations into oligonucleotide lipoplexes, virtually no work has addressed whether the physicochemical properties of these assemblies vary as a function of the constituent oligonucleotide (ODN) sequence and/or composition. The present study was aimed at answering this question.
Meidan, V.M., Glezer, J., Amariglio, N., Cohen, J.S., Barenholz, Y.   +4 more
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Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment

Current Medicinal Chemistry, 2005
In this account we summarise recent studies on oligonucleotides and oligonucleotide derivatives and their utilisation in antigene, antisense and decoy approaches, with particular attention to peptide nucleic acids, locked nucleic acids and oligonucleotide conjugates, the most promising compounds in this field.
DA ROS, TATIANA, SPALLUTO, GIAMPIERO, PRATO, MAURIZIO, SAISON BEHMOARAS T, BOUTORINE A, CACCIARI B.   +5 more
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The Prebiotic Synthesis of Oligonucleotides

Origins of Life, 1974
This paper is primarily a review of recent developments in the abiotic synthesis of nucleotides, short chain oligonucleotides, and their mode of replication in solution. It also presents preliminary results from this laboratory on the prebiotic synthesis of thymidine oligodeoxynucleotides.
E. Stephen-Sherwood, J. Oró
openaire   +3 more sources

Diagnosis with oligonucleotides

Clinics in Dermatology, 1991
Abstract Protein-based immunohistochemical techniques like immunoperoxidase methods are now routinely used in many diagnostic dermatopathology laboratories. This is possible because of the availability of antibodies that react with specific, diagnostically useful proteins and because there are simple but sensitive detection systems.
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Labeling of Oligonucleotides with Fluorescein

Molecular Biotechnology, 1997
The labeling of oligonucleotide probes using a fluorescein-labeled nucleotide is described. The reaction is characterized by careful control of the nucleotide and probe molar ratio in order to produce a tail that gives good detection sensitivity without compromising hybridization stringency control of the probe sequence.
Patricia M. E. Chadwick, Ian Durrant
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Circular Oligonucleotides: New Concepts in Oligonucleotide Design

Annual Review of Biophysics and Biomolecular Structure, 1996
Recent progress in the synthesis and properties of circular oligonucleotides as ligands for DNA and RNA and as templates for polymerase enzymes is described. Small synthetic circular DNAs, RNAs, and chimeric analogues ranging from 28 to 74 nucleotides in size have been synthesized with the use of a nonenzymatic ligation strategy.
openaire   +3 more sources