Results 351 to 360 of about 584,539 (379)

Synthesis of Oligonucleotides and Oligonucleotide Analogues

1989
The aim of this review is to outline modern methods for synthesizing natural oligodeoxynucleotides and certain analogues that may be inhibitors of gene expression. As a consequence, several DNA chemical synthesis methodologies such as the phosphate diester and phosphate triester approaches, which are now primarily only of historical interest, will not ...
openaire   +1 more source

Discrimination of oligonucleotides of different lengths with a wild-type aerolysin nanopore.

Nature Nanotechnology, 2016
C. Cao, Yilun Ying, Zheng-Li Hu, Dong-Fang Liao, H. Tian, Yitao Long   +5 more
semanticscholar   +1 more source

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform.

Annual Review of Pharmacology and Toxicology, 2010
C. Bennett, E. Swayze
semanticscholar   +1 more source

Oligonucleotides

2006
Heidenreich O, Sczakiel G
openaire   +2 more sources

Oligonucleotide

2008
  +4 more sources

The Medicinal Chemistry of Therapeutic Oligonucleotides.

Journal of Medicinal Chemistry, 2016
W. Wan, P. Seth
semanticscholar   +1 more source

Oligonucleotide

2011
openaire   +2 more sources

Phosphorothioates, Essential Components of Therapeutic Oligonucleotides

Nucleic Acid Therapeutics, 2014
F. Eckstein
semanticscholar   +1 more source

Oligonucleotide

2006
openaire   +2 more sources

Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

Science, 1993
C. Stein, Yung‐chi Cheng
semanticscholar   +1 more source