Results 51 to 60 of about 27,967 (201)

Fluorination as a Molecular Design Parameter for Programming Peptide Nanocarriers

Small, EarlyView.
Controlled side‐chain fluorination programs the SA, morphology, and biological performance of amphiphilic fluoropeptide–RGD nanocarriers. A narrow fluorination window yields compact non‐amyloid fibrils with high loading capacity, pH‐triggered release, receptor‐specific uptake, low cytotoxicity, and enzymatic degradability.
Maurizio Iannuzzi, Holly Fiedler, Kilian Haoues, Suvrat Chowdhary, Hossein Batebi, Anil Kumar Sahoo, Andreas F. Thünemann, Boris Schade, Elisa Quaas, Roland R. Netz, Beate Koksch   +10 more
wiley   +1 more source

Identification and Free Radical Scavenging Activity of Oligopeptides from Mixed-Distillate Fermented Baijiu Grains and Soy Sauce Residue

Metabolites
This study aimed to explore the potential antioxidant activity and mechanism of oligopeptides from sauce-aroma Baijiu. The oligopeptides of Val-Leu-Pro-Phe (VLPF), Pro-Leu-Phe (PLF), Val-Gly-Phe-Cys (VGFC), Leu-Tyr-Pro (LYP), Leu-Pro-Phe (LPF), and Phe ...
Yunhao Zhao, Xiangyue Liu, Sijie Zhang, Zhengwei Wang, Shanlin Tian, Qiang Wu   +5 more
doaj   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

The chemoenzymatic synthesis of glycan-terminated oligo(Leu)x

Frontiers in Catalysis
Introduction: Glycopeptides contain carbohydrate moieties (glycans) covalently attached to the side chain and/or terminal peptide units. Since glycans are present on cell surfaces, these constructs can potentially address a wide array of therapeutic ...
Sarah P. Black, Melinda Liu, Cesar Castillo, Wynne Coradeli, Filbert Totsingan, Cody B. Edson, Sagar D. Khare, Richard A. Gross   +7 more
doaj   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

Modulation of gut microbiota and serum metabolome by Apostichopus japonicus derived oligopeptide in high-fructose diet-induced hyperuricemia in mice

Food Science and Human Wellness
Fructose consumption has risen dramatically in recent decades due to the use of sucrose and high fructose corn syrup in beverages and processed foods, contributing to rising rates of hyperuricemia.
Jun Zhou, Ziyan Wang, Zhixuan Zhang, Jiaojiao Han, Ying Feng, Jing Zhang, Zhen Zhang, Ye Li, Tinghong Ming, Chenyang Lu, Rixin Wang, Xiurong Su   +11 more
doaj   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Bacteriostasis and Anti-Inflammation of Staphylococcus epidermidis Fermentation Broth to Propionibacterium acnes

Cosmetics
In this work, Staphylococcus epidermidis (S. epidermidis) fermentation broth with inhibitory effects on the growth of Propionibacterium acnes (P. acnes) and inflammation caused by P. acnes. was obtained. Three kinds of S.
Wenlin Geng, Yun Zhang, Yuhua Cao
doaj   +1 more source

Bio‐active designed peptide for hair keratin strengthening

International Journal of Cosmetic Science, EarlyView.
Bioactive tripeptides through in silico screening revealed KCV (Tripeptide‐132) as the most promising keratin‐targeting candidate. Experimental studies confirmed its superior hair‐strengthening performance with 44% tensile strength enhancement, 50% breakage reduction, improved surface integrity and fibre penetration.
Chan‐Su Rha, Byeong Gyu In, Kilsun Myoung, Chaeyeon Song, Eun‐Soo Lee, Heung Soo Baek, Won Seok Park   +6 more
wiley   +1 more source

IN VITRO INDUCTION OF BLOOD MONONUCLEAR CELL PROLIFERATION BY ENDOGENOUS RETROVIRAL HERV-Eλ4-1 ENVELOPE PEPTIDE IN PATIENTS WITH MULTIPLE SCLEROSIS

Медицинская иммунология, 2014
A comparative in vitro study of blood mononuclear cells from multiple sclerosis patients and healthy donors was performed, in order to evaluate proliferative response to a retroviral antigen, aiming to determine immunomodulatory properties of synthetic ...
A. A. Smagin, I. A. Goldina, K. V. Gaidul, M. S. Lubarsky   +3 more
doaj   +1 more source