Results 141 to 150 of about 22,170 (201)
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Pepstatin A: Polymerization of an oligopeptide
Micron, 1994Pepstatin A, a pentapeptide with the molecular weight of 686, is a naturally occurring inhibitor of aspartyl proteases secreted by Streptomyces species. Above a critical concentration of 0.1 mM at low ionic strength and neutral pH, it can polymerize into filaments which may extend over several micrometers.
Mothes, E., Shoeman, R., Traub, P.
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Interaction of Oligopeptides with Heparin
Macromolecular Symposia, 1998Macromolecular drugs, such as heparin and insulin, are easily degraded by acids and enzymes in the GI tract and do not readily penetrate the lipophilic biomembranes, resulting in low bioavailability by the oral route.1–3 Currently, these drugs have to be administered by injections. Proteinoids,4–8 which can form microspheres with certain macromolecular
Ruifeng Zhao +2 more
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EFFECT OF SYNTHETIC OLIGOPEPTIDES ON OSTEOPOROSIS
Preparative Biochemistry & Biotechnology, 2002The objective of this study was to establish the solution method of GHRPS, the synthetic oligopeptides Tyr-Gly-Gly-Phe-Met-NH2, Tyr-Gly-Gly-Phe-Met-OH, Tyr-Gly-Gly-Phe-Leu-NH2, Tyr-Gly-Gly-Phe-Leu-OH, Tyr-Gly-Gly-Phe-Gly-NH2, and Tyr-Gly-Gly-Phe-Gly-OH, to verify their effect on osteoporosis. Male ICR mice (20+/-2 g) were used.
Cui, Weina +3 more
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Oligopeptides as Catalysts for Asymmetric Epoxidation
ChemInform, 2005AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
David R, Kelly, Stanley M, Roberts
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The role of oligopeptides in preventing autism
Medical Hypotheses, 2020Previous reports in this series point to insufficient insulin-like growth factor-1 (IGF1) in the newborn as the key to brain dysconnectivity characteristic of autism. Such a deficiency should be detectable in the baby's blood at or soon after birth. Breast-feeding exclusively for the first year of postpartum life or supplementation with oral agents to ...
Gary, Steinman, David, Mankuta
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Russian Chemical Bulletin, 2019
The paper presents the results concerning the use of the supercomputer docking program SOL-P, which performs a search for low-energy minima of protein—ligand complexes in the MMFF94 force field without using a grid of precalculated potentials for protein—ligand interactions. The SOL-P docking program can be applied to the generalized docking of ligands
A. V. Sulimov +6 more
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The paper presents the results concerning the use of the supercomputer docking program SOL-P, which performs a search for low-energy minima of protein—ligand complexes in the MMFF94 force field without using a grid of precalculated potentials for protein—ligand interactions. The SOL-P docking program can be applied to the generalized docking of ligands
A. V. Sulimov +6 more
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Molecular Radical Cations of Oligopeptides
The Journal of Physical Chemistry B, 2000An unprecedented method of producing molecular radical cations of oligopeptides in the gas phase has been discovered. Electrospraying a methanolic mixture of a Cu(II)−amine complex, e.g., CuII(dien)(NO3)2 (where dien = diethylenetriamine), and an oligopeptide (M) yields the [CuII(dien)M]•2+ ion, whose collision-induced dissociation (CID) produces [CuI ...
Hopkinson, AC +4 more
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Self-Assembly of Homo Phenylalanine Oligopeptides: Role of Oligopeptide Chain Length
LangmuirThe self-assembly of phenylalanine (F)-based peptides is a critical area of research with potential implications for the development of advanced biomaterials and technologies. Previous studies indicate that homo-oligopeptides with F-X residues (X = 1 to 6) can self-assemble into diverse nano-microstructures, but the role of oligopeptide chain length on
Safaa Kader +2 more
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Oligopeptides in the formation of biological motivations
Neuroscience and Behavioral Physiology, 19871. Oligopeptides participate in the organization of eating and defense behavior and self-stimulation. 2. The majority of the investigated oligopeptides when injected into the lateral ventricles have an inhibitory influence on the manifestation of biological motivations.
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