Results 71 to 80 of about 9,493 (210)

Elevated CD4+, CD8+, and Pro-inflammatory Cytokine Levels and H19 Hypomethylation are Associated with Reduced Sperm Motility in Oligoasthenoteratozoospermia: A Case-control Study

open access: yesDubai Medical Journal
Introduction: Oligoasthenoteratozoospermia (OAT) is a frequent cause of male reproductive issues, but its etiology remains unclear. This study investigated the associations between immune markers, epigenetic alterations, and sperm parameters in men with
Rehab Sh. Al-Maliki
doaj   +1 more source

Spata19 Inactivation as a Cause of Oligospermia

open access: yesResearch in Molecular Medicine, 2021
Background: Spermatogenesis associated 19 (Spata19) was introduced as a testis-specific gene that was probably involved in spermatogenesis cell apoptosis.
Mahsa Zargar   +6 more
doaj  

Engineering Decavalent, Sperm‐Binding Laminin‐IgG Hybrid Antibodies for Potent Non‐Hormonal Contraception

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer   +8 more
wiley   +1 more source

Update on male reproductive endocrinology. [PDF]

open access: yes, 2018
Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
core   +1 more source

Gut Microbial Genetic Variation Regulates Host Reproduction

open access: yesMicrobial Biotechnology, Volume 18, Issue 10, October 2025.
We discovered that microbial genetic variation interacts with host genetics to regulate host reproduction. We identified E. coli mutants that mitigate cyclophosphamide‐induced male reproductive toxicity and found that the purine metabolism pathway may contribute to it.
Xiaoyue Ding   +11 more
wiley   +1 more source

Artificial Insemination in the Human [PDF]

open access: yes, 1972
The idea that impregnation might occur without coitus has aroused interest since ancient times. In the second century A.D., there was recorded a hypothetical discussion concerning a woman who had been inseminated by semen previously deposited in the bath
Board, John A.
core   +1 more source

Complications of Cushing's syndrome: state of the art [PDF]

open access: yes, 2016
Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and excessive secretion of cortisol. The syndrome is associated with increased mortality and impaired quality of life because of the occurrence of comorbidities.
Biller, Beverly M. K   +5 more
core   +1 more source

Compound Heterozygous Variants in ZSWIM7 Gene Linked to Infertility and Its Role in Gonadal Development

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 9, September 2025.
ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini   +8 more
wiley   +1 more source

Evidence-based investigations for subfertility [PDF]

open access: yes, 2014
published_or_final_versio
Chai, J, Ng, EHY
core  

Microcystin-leucine arginine causes cytotoxic effects in sertoli cells resulting in reproductive dysfunction in male mice [PDF]

open access: yes, 2016
2016-2017 > Academic research: refereed > Publication in refereed journal201804_a bcmaVersion of ...
Chen, YB   +6 more
core   +1 more source

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