Results 11 to 20 of about 251 (83)

An allene oxide and 12-oxophytodienoic acid are key intermediates in jasmonic acid biosynthesis by Fusarium oxysporum [PDF]

Journal of Lipid Research, 2017
Fungi can produce jasmonic acid (JA) and its isoleucine conjugate in large quantities, but little is known about the biosynthesis. Plants form JA from 18:3n-3 by 13S-lipoxygenase (LOX), allene oxide synthase, and allene oxide cyclase. Shaking cultures of
Ernst H. Oliw, Mats Hamberg
doaj   +2 more sources

A network model for human playfulness during war [PDF]

Scientific Reports
This novel study investigates adult playfulness during recent wartime in the Middle East using the OLIW model of playfulness and the concept of fantastic reality ability to utilize imagination in response to stress and trauma.
Dori Rubinstein, Mooli Lahad, Limor Aharonson-Daniel, Kay Brauer, René T. Proyer   +4 more
doaj   +2 more sources

Fungal oxylipins direct programmed developmental switches in filamentous fungi [PDF]

Nature Communications, 2020
Fungi produce oxygenated fatty acids, or oxylipins, of unclear function. Here, Niu et al. show that an Aspergillus oxylipin induces various developmental processes in several fungi, including lateral branching in human pathogenic Aspergillus species, and
Mengyao Niu, Breanne N. Steffan, Gregory J. Fischer, Nandhitha Venkatesh, Nicholas L. Raffa, Molly A. Wettstein, Jin Woo Bok, Claudio Greco, Can Zhao, Erwin Berthier, Ernst Oliw, David Beebe, Michael Bromley, Nancy P. Keller   +13 more
doaj   +2 more sources

Manganese lipoxygenase of F. oxysporum and the structural basis for biosynthesis of distinct 11-hydroperoxy stereoisomers [PDF]

Journal of Lipid Research, 2015
The biosynthesis of jasmonates in plants is initiated by 13S-lipoxygenase (LOX), but details of jasmonate biosynthesis by fungi, including Fusarium oxysporum, are unknown. The genome of F.
Anneli Wennman, Ann Magnuson, Mats Hamberg, Ernst H. Oliw   +3 more
doaj   +2 more sources

Discovery of a linoleate 9S-dioxygenase and an allene oxide synthase in a fusion protein of Fusarium oxysporum[S] [PDF]

Journal of Lipid Research, 2013
Fusarium oxysporum is a devastating plant pathogen that oxidizes C18 fatty acids sequentially to jasmonates. The genome codes for putative dioxygenase (DOX)-cytochrome P450 (CYP) fusion proteins homologous to linoleate diol synthases (LDSs) and the ...
Inga Hoffmann, Ernst H. Oliw
doaj   +2 more sources

A new class of fatty acid allene oxide formed by the DOX-P450 fusion proteins of human and plant pathogenic fungi, C. immitis and Z. tritici[S] [PDF]

Journal of Lipid Research, 2016
Linoleate dioxygenase-cytochrome P450 (DOX-CYP) fusion enzymes are common in pathogenic fungi. The DOX domains form hydroperoxy metabolites of 18:2n-6, which can be transformed by the CYP domains to 1,2- or 1,4-diols, epoxy alcohols, or to allene oxides.
Ernst H. Oliw, Marc Aragó, Yang Chen, Fredrik Jernerén   +3 more
doaj   +2 more sources

Epoxy alcohol synthase of the rice blast fungus represents a novel subfamily of dioxygenase-cytochrome P450 fusion enzymes[S] [PDF]

Journal of Lipid Research, 2014
The genome of the rice blast fungus Magnaporthe oryzae codes for two proteins with N-terminal dioxygenase (DOX) and C-terminal cytochrome P450 (CYP) domains, respectively.
Inga Hoffmann, Fredrik Jernerén, Ernst H. Oliw   +2 more
doaj   +2 more sources

Crystal structure of linoleate 13R-manganese lipoxygenase in complex with an adhesion protein1 [PDF]

Journal of Lipid Research, 2016
The crystal structure of 13R-manganese lipoxygenase (MnLOX) of Gaeumannomyces graminis (Gg) in complex with zonadhesin of Pichia pastoris was solved by molecular replacement. Zonadhesin contains β-strands in two subdomains.
Yang Chen, Anneli Wennman, Saeid Karkehabadi, Åke Engström, Ernst H. Oliw   +4 more
doaj   +2 more sources

Role of Seminal Exosomes in Reproduction [PDF]

Journal of Cellular Physiology, Volume 240, Issue 11, November 2025.
ABSTRACT Exosomes are small lipid bilayer vesicles, ranging from 30 to 150 nm in diameter, that are secreted by various cells and facilitate intercellular communication. They originate from the endosomal system and release their contents into the extracellular environment.
Shayesteh Mehdinejadiani, Nahid Azad, Zeinab Dehghan, Zahra Khosravizadeh, Fatemeh Saberi, Delsuz Rezaee, Tayyebeh Pilehchi, Nasim Goudarzi, Elnaz Salahi, Kobra Mehdinejadiani   +9 more
wiley   +2 more sources

Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases [PDF]

Journal of Lipid Research, 2011
Seven Z-octadecenoic acids having the double bond located in positions 6Z to 13Z were photooxidized. The resulting hydroperoxy-E-octadecenoic acids [HpOME(E)] were resolved by chiral phase-HPLC-MS, and the absolute configurations of the enantiomers were ...
Ernst H. Oliw, Anneli Wennman, Inga Hoffmann, Ulrike Garscha, Mats Hamberg, Fredrik Jernerén   +5 more
doaj   +2 more sources