Results 81 to 90 of about 1,458 (206)

Formulation and Evaluation of Olopatadine Hydrochloride Opthalmic Solution

Olopatadine Hydrochloride is a selective histamine H1-receptor antagonist and mast cell stabilizer widely used in the treatment of allergic conjunctivitis.
YogeshSharma, Deepak koshti, Ramdarshan Parashar, VaibhavRajoriya, Akansha Athiya, Ajay Singh Thakur   +5 more
core   +1 more source

Olopatadine 0.6% nasal spray protects from vasomotor challenge in patients with severe vasomotor rhinitis

, 2011
Background: Vasomotor rhinitis (VMR) is a hypersensitivity syndrome with heightened reactivity to environmental triggers. Methods: Twenty-two patients with severe VMR were treated nasally with either normal saline or 0.6% olopatadine and challenged ...
Collins, Joel, Peter K. Smith, Smith, Peter K, Smith, Peter, Joel Collins   +4 more
core   +1 more source

Comparative study of the efficacy and safety of olopatadine eyedrops and sodium cromoglycate in clinical practice: a prospective study [PDF]

, 2016
Background: Allergic eye diseases are the commonest causes of ocular morbidity worldwide. To choose the best therapy in allergic conjunctivitis, understanding of underlying mechanisms implicated in triggering the allergy is very important.
Scandashree K, Udaykumar, Padmaja, Padmaja Udaykumar, Meghana Patil, Patil, Meghana, K., Scandashree   +5 more
core   +1 more source

A multicenter evaluation of the efficacy and duration of action of alcaftadine 0.25% and olopatadine 0.2% in the conjunctival allergen challenge model

Journal of Asthma and Allergy, 2013
Stacey Ackerman,1 Francis D’Ambrosio Jr,2 Jack V Greiner,3 Linda Villanueva,4 Joseph B Ciolino,5 David A Hollander41Philadelphia Eye Associates, Philadelphia, PA, 2D’Ambrosio Eye Care, Lancaster, MA, 3Schepens Eye Research Institute ...
Ackerman S, D'Ambrosio, Jr F, Greiner JV, Villanueva L, Ciolino JB, Hollander DA   +6 more
doaj  

Topical Use of Olopatadine and Cyclosporine a in Treatment of Vernal Keratoconjunctivitis

, 2016
Aim: To compare the efficacy and safety of Olopatadine hydrochloride (0.1%) with Cyclosporine A ophthalmic solution (0.05%) in treating the signs and symptoms of VKC. Material and Method: Twenty-five patients with VKC were included in a prospective study.
Fikret, Akata, Zaure, Knatova, Eugeniu, Vieru, Aylin, Kantarci Feride   +3 more
core   +1 more source

Effects of olopatadine hydrochloride on the release of thromboxane B2 and histamine from nasal mucosa after antigen–antibody reaction in guinea pigs [PDF]

, 2001
BackgroundVarious mediators, such as thromboxane (TX) A2, peptide leukotrienes (P-LT) and histamine, are involved in allergic nasal obstruction. The aim of the present study was to investigate the mechanism whereby olopatadine hydrochloride, a novel anti-
Ishii, Akio, Karasawa, Akira, Ohmori, Kenji, Kaise, Toshihiko, Akamatsu, Yukino   +4 more
core   +1 more source

Efficacy and Toxicity Evaluation of Bepotastine Besilate 1.5% Preservative-Free Eye Drops Vs Olopatadine Hydrochloride 0.2% Bak-Preserved Eye Drops in Patients with Allergic Conjunctivitis

Clinical Ophthalmology, 2023
María Cecilia Marini,1 Martín Lucas Berra,2 Fernada Girado,3 Paula Alejandra Albera,4 Melina Sol del Papa,5 María Silvia Passerini,5 Alejandro Javier Aguilar6 1Ophthalmology Service, El Cruce-Nestor Kirchner High Complexity Hospital, Buenos Aires ...
Marini MC, Berra ML, Girado F, Albera PA, del Papa MS, Passerini MS, Aguilar AJ   +6 more
doaj  

Olopatadine Exerts Multifaceted Protective Effects in an Ovalbumin-Induced Allergic Eye Disease Mouse Model

Bioengineering
Allergic eye disease (AED), including allergic conjunctivitis, is a prevalent immune-mediated disorder of the ocular surface characterized by itching, redness, tearing, and ocular discomfort.
Basanta Bhujel, Kyu Sang Eah, Soon Suk Kang, Ho Seok Chung, Hun Lee, Jae-Yong Kim   +5 more
doaj   +1 more source

Olopatadine: a drug for allergic conjunctivitis targeting the mast cell

, 2010
IMPORTANCE OF THE FIELD: Ocular allergic diseases are characterized by specific activation of conjunctival mast cells with subsequent release of preformed and newly formed mediators.
LEONARDI, ANDREA, QUINTIERI, LUIGI
core   +1 more source

Efficacy of Tacrolimus 0.03% Ointment Vs. Olopatadine 0.2% Eye Drops in Vernal Keratoconjunctivitis: A Comparative Study

Pakistan Journal of Medicine and Dentistry
Background: Vernal keratoconjunctivitis (VKC) is a chronic, vision-threatening eye inflammation typically starting in early childhood and often resolving by puberty, though it can begin earlier and persist into adulthood. This study aimed to evaluate the
Maria Sultan, Syed Amir Hamza, Maleeha Safdar Ali , Muhammad Tariq   +3 more
doaj   +1 more source