Long-term efficacy and safety of erenumab in Japanese patients with episodic and chronic migraine: results from a 28-week open-label treatment period of a randomised trial [PDF]
Objectives To evaluate the 1-year efficacy and safety of once-monthly erenumab 70 mg following a 24-week double-blind treatment period (DBTP) of a phase III randomised study of Japanese patients with episodic migraine (EM) or chronic migraine (CM).Design
Koichi Hirata +9 more
doaj +2 more sources
Thespis: Causally-consistent OLTP [PDF]
Data Consistency defines the validity of a data set according to some set of rules, and different levels of data consistency have been proposed. Causal consistency is the strongest type of consistency possible when data is stored in multiple locations, and fault tolerance is desired.
Carl Camilleri +2 more
doaj +3 more sources
Arthroscopic Bone Marrow Stimulation or Non-Operative Treatment for Osteochondral Lesions of the Tibial Plafond [PDF]
Category: Ankle; Arthroscopy Introduction/Purpose: A paucity of clinical results from osteochondral lesion of the tibial plafond (OLTP) treatment exists in the literature.
Quinten Rikken +3 more
doaj +2 more sources
Safety, Efficacy, and Patient‐Reported Outcomes From a Phase 2 Randomized Trial of Pozelimab and Cemdisiran Combination in Patients With Paroxysmal Nocturnal Hemoglobinuria [PDF]
Introduction Paroxysmal nocturnal hemoglobinuria (PNH) is an ultra‐rare, life‐threatening disease associated with chronic intravascular hemolysis due to uncontrolled complement activation.
Jun‐Ho Jang +12 more
doaj +2 more sources
Osteotomy and Filling for Osteochondral Lesions of the Tibial Plafond: A Novel Morphology Based Surgical Technique [PDF]
Category: Ankle Introduction/Purpose: Symptomatic primary (large) cystic and non-primary osteochondral lesions of the medial and central tibial plafond are challenging entities to treat. These lesions may benefit from a lesion specific treatment approach.
Quinten Rikken MD +4 more
doaj +2 more sources
Osteochondral Lesions of the Tibial Plafond: A Restorative Procedure for Cystic Defects [PDF]
Background: Osteochondral lesions of the tibia plafond (OLTPs) are an uncommon problem that can generate pain. Indications: Arthroscopic techniques can provide symptomatic relief and improved outcomes when conservative management has failed.
Francis Bustos MD, Richard Ferkel MD
doaj +2 more sources
Osteochondral lesion of the tibial plafond treated with a retrograde osteochondral autograft: a report of two cases [PDF]
Background: Osteochondral lesions (OCLs) of the tibial plafond (OLTPs) are rare, and few studies provide treatment recommendations. We describe two cases of an OLTP that were treated with retrograde osteochondral autograft.
Kensuke Okamura +6 more
doaj +2 more sources
MULTIDIMENSIONAL DATABASES IN INFORMATION SYSTEMS OF UNIVERSITIES [PDF]
The article is devoted to the description of the method of multidimensional database, which is an effective method of data storage, which allows analyzing data qualitatively, and most importantly in a short time.
A. Mukasheva, D. Yedilkhan, M. Aldiyar
doaj +1 more source
Electronic medical record (EMR) data vary between institutions. These data should be converted into a common data model (CDM) for multi-institutional joint research. To build the CDM, it is essential to integrate the EMR data of each hospital and load it
Tong Min Kim +5 more
doaj +1 more source
Research and implementation of HTAP for distributed database
Data processing can be roughly divided into two categories, online transaction processing OLTP(on-line transaction processing) and online analytical processing OLAP(on-line analytical processing).
doaj +1 more source

