Results 41 to 50 of about 458,544 (254)

Electrodynamics of an omega-band as deduced from optical and magnetometer data [PDF]

open access: yes, 2009
We investigate an omega-band event that took place above northern Scandinavia around 02:00–02:30 UT on 9 March 1999. In our analysis we use ground based magnetometer, optical and riometer measurements together with satellite based optical images.
A. Senior   +11 more
core   +2 more sources

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

A Review of the Effects of Omega-3 and Omega-6 on Alcoholic and Non-Alcoholic Fatty Liver [PDF]

open access: yes
Non-alcoholic fatty liver disease (NAFLD) is characterized by fat accumulation in the liver not caused by excessive alcohol consumption. In contrast, alcoholic liver disease (ALD) is directly caused by it.
Darvishi, Mohammad   +6 more
core   +1 more source

Biosynthesis of highly unsaturated fatty acids by hydrocarbon degrading microorganisms [PDF]

open access: yesJournal of BioScience and Biotechnology, 2015
Disruption of polyunsaturated fatty acids (PUFA) metabolism leads to many diseases. In this study, producers of γ-linolenic acid (GLA), arachidonic acid (ARA) and eicosapentaenoic acid (EPA) were selected: Cephalosporium humicola IE (on glucose, dry ...
MEHDI GHASEMI, YEMEN ATAKISHIYEVA
doaj  

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Investigation of the Causal Association between Long-Chain n-6 Polyunsaturated Fatty Acid Synthesis and the Risk of Type 2 Diabetes: A Mendelian Randomization Analysis

open access: yesLifestyle Genomics, 2020
Background: Globally, 1 in 11 adults has diabetes mellitus, and most of these cases are type 2 diabetes (T2D). The risk of T2D is influenced by many factors, including diet.
Michael A. Zulyniak   +2 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study

open access: yesBMC Geriatrics, 2022
Background Frailty is a geriatric syndrome associated with disability and negative health outcome. To determine the factors associated with frailty and functional disability in older participants living in community in France.
Achille Tchalla   +9 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Mesoscale ionospheric electrodynamics of omega bands determined from ground-based electromagnetic and satellite optical observations [PDF]

open access: yes, 2005
International audienceWe present ground-based electromagnetic data from the MIRACLE and BEAR networks and satellite optical observations from the UVI and PIXIE instruments on the Polar satellite of an omega band event over Northern Scandinavia on 26 June
Viljanen, A.   +17 more
core   +2 more sources

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