Results 111 to 120 of about 407,505 (399)

Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges

Journal of Analytical Science and Technology
Mass spectrometry (MS)-based intact mass analysis and structural characterization of biotherapeutic proteins such as monoclonal antibodies (mAbs) are a crucial characterization approach from upstream drug development to downstream product analysis.
Abhik Mojumdar, Hee-Jin Yoo, Duck-Hyun Kim, Jiwon Park, Su-Jin Park, Eunji Jeon, Sunhee Choi, Jung Hoon Choi, Moonhee Park, Geul Bang, Kun Cho   +10 more
doaj   +1 more source

High-throughput verification of transcriptional starting sites by Deep-RACE

BioTechniques, 2009
We present a high-throughput method for investigating the transcriptional starting sites of genes of interest, which we named Deep-RACE (Deep–rapid amplification of cDNA ends).
Signe Olivarius, Charles Plessy, Piero Carninci   +2 more
doaj   +1 more source

IOBR: Multi-Omics Immuno-Oncology Biological Research to Decode Tumor Microenvironment and Signatures

bioRxiv, 2020
Motivation Recent advance in next generation sequencing has triggered the rapid accumulation of publicly available multi-omics datasets. The application of integrated omics to exploring robust signatures for clinical translation is increasingly ...
D. Zeng, Zilan Ye, Guangchuang Yu, Jiani Wu, Yi Xiong, R. Zhou, Wenjun Qiu, N. Huang, Li Sun, J. Bin, Y. Liao, Min Shi, W. Liao   +12 more
semanticscholar   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Pathway Tools version 23.0: Integrated Software for Pathway/Genome Informatics and Systems Biology

, 2019
Pathway Tools is a bioinformatics software environment with a broad set of capabilities. The software provides genome-informatics tools such as a genome browser, sequence alignments, a genome-variant analyzer, and comparative-genomics operations.
Billington, Richard, Caspi, Ron, Karp, Peter D., Keseler, Ingrid M., Kothari, Anamika, Krummenacker, Markus, Midford, Peter E., Ong, Wai Kit, Paley, Suzanne M., Subhraveti, Pallavi   +9 more
core  

Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes

, 2022
Maria Fasolino, Gregory W. Schwartz, Abhijeet R. Patil, Aanchal Mongia, Maria L. Golson, Yue J. Wang, Ashleigh Morgan, Chengyang Liu, Jonathan Schug, Jinping Liu, Minghui Wu, Daniel Traum, Ayano Kondo, Catherine Lee May, Naomi Goldman, Wenliang Wang, Michael D. Feldman, Jason H. Moore, Alberto Sada Japp, Michael R. Betts, Maria Fasolino, Gregory W. Schwartz, Abhijeet R. Patil, Aanchal Mongia, Maria L. Golson, Yue J. Wang, Ashleigh Morgan, Chengyang Liu, Jonathan Schug, Jinping Liu, Minghui Wu, Daniel Traum, Ayano Kondo, Catherine Lee May, Naomi Goldman, Wenliang Wang, Michael D. Feldman, Jason H. Moore, Alberto Sada Japp, Michael R. Betts, Robert B. Faryabi, Ali Naji, Klaus H. Kaestner, Golnaz Vahedi, Robert B. Faryabi, Ali Naji, Klaus H. Kaestner, Golnaz Vahedi   +47 more
openalex   +2 more sources

Omics in immunology [PDF]

Immunology & Cell Biology, 2021
Samuel, Foster, Fabio, Luciani
openaire   +2 more sources

Laser‐Microscribed Glass Enables Surface‐Microfluidics‐Facilitated, Affordable, Rapid Cancer Diagnosis

Advanced Functional Materials, EarlyView.
A transparent, laser‐microscribed glass platform enables cancer diagnosis within 1 h—much faster than histology, which takes days, and free from the chemical or contrast risks of MRI or CT scans. The antibody‐functionalized rough glass surface captures viable cancer cells directly from suspension, allowing instant optical readout and offering a rapid ...
Anish Pal, Snehasis Mishra, Arani Mukhopadhyay, Ilias Papailias, Atique U. Ahmed, Constantine M. Megaridis   +5 more
wiley   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Integrating Molecular Perspectives: Strategies for Comprehensive Multi-Omics Integrative Data Analysis and Machine Learning Applications in Transcriptomics, Proteomics, and Metabolomics

Biology
Simple Summary Recent high-throughput technologies such as transcriptomics, proteomics, and metabolomics have allowed progress in understanding biological systems at different levels of detail.
P. Sanches, Nicolly Clemente de Melo, A. Porcari, L. M. de Carvalho   +3 more
semanticscholar   +1 more source