Results 191 to 200 of about 407,505 (399)

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source

P678: Role of de novo variants in genetic disorders with new insights and clinical implications

Genetics in Medicine Open
Babi Ramesh Reddy Nallamilli, Mary Colasanto, Ruby Liu, Naga Guruju, Lakshmanan Jagannathan, Arul Joseph Duraisamy, Jorune Balciuniene, Xiangwen Chen-Deutsch, Rizwan Yousaf, Christin Collins, Lora Bean, Supan Dhillon, Cristina da Silva, Madhuri Hegde   +13 more
doaj   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

P679: Ultrarapid whole genome sequencing facilitates early definitive diagnosis of rare genetic disorders

Genetics in Medicine Open
Babi Ramesh Reddy Nallamilli, Jagannathan Lakshmanan, Vinish Ramachander, Supan Dhillon, Ruby Liu, Yinghong Pan, Naga Guruju, Christin Collins, Lora Bean, Madhuri Hegde   +9 more
doaj   +1 more source

Single cell analysis: the new frontier in 'Omics'

, 2010
Daojing Wang, Steven Bodovitz
openalex   +2 more sources

Deciphering Tumor Heterogeneity in Hepatocellular Carcinoma (HCC)—Multi-Omic and Singulomic Approaches [PDF]

, 2021
Renumathy Dhanasekaran
openalex   +1 more source

Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap

Nature Protocols, 2019
J. Reimand, Ruth Isserlin, V. Voisin, Mike Kucera, Christian Tannus-Lopes, Asha Rostamianfar, Lina Wadi, Mona Meyer, Jeff Wong, Changjiang Xu, D. Merico, Gary D Bader   +11 more
semanticscholar   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

P053: Understanding the measurement of nicotinamide adenine dinucleotide (NAD+) from dried blood spots through a population study

Genetics in Medicine Open
Sara Smith, Madeline Ellgass, Ariana Park, Alexah Kaib, Haley Lindberg, Christopher Burns, Taraka Donti, P.J. Borandi, Madhuri Hegde   +8 more
doaj   +1 more source

Plant Organellar Omics

, 2022
Kanai, Masatake, Tamura, Kentaro, Tarnawska-Glatt, Katarzyna, Yamada, Shino, Yamada, Kenji, Mano, Shoji   +5 more
openaire   +2 more sources