Results 271 to 280 of about 407,505 (399)

A dynamic characterization of efficiency [PDF]

, 2009
Stefanou, S.E.
core  

Table 2_Multi-omics analysis reveals ultraviolet response insights for immunotherapy and prognosis.docx

DanHua Zhang (22315099), Mei Dai (3105909), JiaFei Ying (22315102), YiFan Huang (22315105), ZiXuan Liu (22315108), ChenLu Wu (22315111)   +5 more
openalex   +1 more source

Vector-omics? [PDF]

Molecular Therapy, 2004
openaire   +2 more sources

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

Melatonin-enabled omics: understanding plant responses to single and combined abiotic stresses for climate-smart agriculture. [PDF]

GM Crops Food
Raza A, Li Y, Charagh S, Guo C, Zhao M, Hu Z.   +5 more
europepmc   +1 more source

Utilising omics approaches to understand Kaposi's sarcoma-associated herpesvirus [PDF]

, 2015
Christopher B. Owen
openalex  

Autopolyploidization‐Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa

Advanced Science, EarlyView.
This study demonstrates that monoploid, diploid, and autotetraploid Brassica rapa lines derived from the same genome exhibit distinct leaf morphology. Ploidy changes remodel chromatin accessibility and histone modifications to regulate gene expression, while key transcription factors BrGRF13 and BrARF11 control leaf size and polarity, driving ...
Haoyuan Dong, Yanhong Liu, Yuanming Liu, Shuxin Xuan, Huanhuan Chen, Lai Wei, Guibao Zhang, Hongcui Pei, Zilong Dai, Yanhua Wang, Jinzhu Qiao, Shuangxia Luo, Xueping Chen, Yiguo Hong, Jianjun Zhao, Shuxing Shen, Zefu Lu, Aixia Gu   +17 more
wiley   +1 more source

MouseOmics: a multi-omics database for mouse biological study. [PDF]

Nucleic Acids Res
Tian X, Teng Y, Huang M, Zhang Q, Huang J, Chen Y, Wu A, Wang Q, Yu J, Feng J.   +9 more
europepmc   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Bridging ancient wisdom and modern technology: an AI and multi-omics framework for three causes tailored treatment in personalized medicine. [PDF]

Front Mol Biosci
Diao X, Zhang H, Wang S, Zhang Q, Wang Z.   +4 more
europepmc   +1 more source