Results 311 to 320 of about 407,505 (399)

Supplementary Material for “Multi-omics Approach Identifies Antidepression Mechanism Variations Between Chaihu Shugan San and Hypericum perforatum L.”

jingxuan tan, Linjie Li, Xixuan Li, Xuemei Han, Deng, Bin, Yanjie Qin, Zhang, Yu, Xuejia Zhai, Yongning Lu   +8 more
openalex   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Liver fibrosis and cirrhosis in the multi-omics era: mechanisms and therapeutic perspectives from human and animal models. [PDF]

Front Cell Infect Microbiol
Lu W, Xu J, Xu Y, Zhou Y, Que S, Liu Z.
europepmc   +1 more source

Image 5_Multi-omics insights into biomarkers of breast cancer associated diabetes: a computational approach.jpeg

Tamizhini Loganathan (18538349), C. George Priya Doss (8130954)   +1 more
openalex   +1 more source

Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA

Advanced Science, EarlyView.
We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang, Yunyun An, Mengqi Yang, Yuqi Pan, Xiaoyi Liu, Fanglei Gong, Huizhen Lin, Bianbian Tang, Yunxia Bai, Xin Zhao, Yu Zhao, Changzheng Du, Kun Sun   +12 more
wiley   +1 more source

LOSTdb: a manually curated multi-omics database for lung cancer research. [PDF]

BMC Bioinformatics
Luo H, Yang Y, Gong Z, Liu L, Chen Y.
europepmc   +1 more source

Live-Cell Monitoringand Omics Analysis of Liquid–SolidTransitions of Biomolecular Condensates

Asmaa M.A.S. Farrag (22354091), Koshiro Ota (19731230), Hideaki Yoshimura (1444879), Misao Takemoto (1830409), Takuma Mitarai (22354094), Takuya Kamikawa (22354097), Masahiro Abo (716769), Vaibhav Pal Singh (16985380), Changyi Cui (287752), Lu Zhou (230418), Fumiyoshi Ishidate (107263), Takahiro Fujiwara (849301), Shin-ichi Sato (1452955), Yuichiro Hori (1921720), Takeaki Ozawa (7500), Kazuya Kikuchi (493555), Motonari Uesugi (509631)   +16 more
openalex   +1 more source

Meta‐GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility

Advanced Science, EarlyView.
This study incorporated 14 210 individuals to perform a GWAS meta‐analysis of six semen quality traits. The GWAS meta‐analysis identifies 234 GWAS loci associated with semen quality traits. The incorporation with a functional genomics resource explains potential genetic regulation of ∼40% GWAS signals underlying semen quality traits.
Qing Lin, Xiaodian Cai, Zhanming Zhong, Tingting Li, Xinyou Chen, Wondossen Ayalew, Zhiting Xu, Chen Wei, Xiaoke Zhang, Hong Cheng, Zhenyang Zhang, Xuehua Li, Yongjie Tang, Siqian Chen, Jun Zhou, Jinglei Si, Xibo Wu, Chao Ning, Qishan Wang, Yuchun Pan, Yahui Gao, Jiaqi Li, Ying Yu, Zhe Zhang, Yunxiang Zhao, Lingzhao Fang, Zhe Zhang   +26 more
wiley   +1 more source

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

Advanced Science, EarlyView.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang, Weihua Pan, Runtian Gao, Heng Hu, Wentao Gao, Murong Zhou, Yu‐Hang Yin, Zhipeng Qian, Shuilin Jin, Guohua Wang   +9 more
wiley   +1 more source

OmNI: a modular open-source framework for interactive multi-omics data integration and visualization. [PDF]

NAR Genom Bioinform
Potter G, Beierle JA, Bryant C, Phanse S, White C, Emili A, Paul I.   +6 more
europepmc   +1 more source