Results 31 to 40 of about 6,728,299 (247)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Medical Negligence with Special Reference to Act of Commission and Omission: A Narrative Review [PDF]
Journal of Clinical and Diagnostic ResearchA doctor’s failure to uphold the standards of his profession, causing the death of a patient whom the doctor hoped to save, is known as medical negligence.
Devesh Nagpure +4 more
doaj +1 more source
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A note on the Wilcoxon-Mann-Whitney test and tied observations.
PLoS ONERecently, it was recommended to omit tied observations before applying the two-sample Wilcoxon-Mann-Whitney test McGee M. et al. (2018). Using a simulation study, we argue for exact tests using all the data (including tied values) as a preferable ...
Markus Neuhäuser, Graeme D Ruxton
doaj +1 more source
Risk behaviors for eating disorder in adolescents and adults with type 1 diabetes
Brazilian Journal of Psychiatry, 2013 Objective: To evaluate the frequency of risk behaviors for eating disorder (ED) in patients with type 1 diabetes (T1D) and their association with gender, nutritional status, variables related to T1D, and body satisfaction.
Sonia Tucunduva Philippi +3 more
doaj +1 more source
BMC Psychiatry, 2020 Background Lead is known to be associated with attention-deficit/hyperactivity disorder (ADHD) even at low concentrations. We aimed to evaluate neurocognitive functions associated with lead in the blood and the interactions between lead and dopaminergic ...
Jae-Won Choi +7 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
ERROR ANALYSIS ON THE AUXILIARY VERBS MADE BY THE TENTH GRADERS OF MAN 2 SAMARINDA
Lingua: Jurnal Bahasa, Sastra dan Pengajarannya, 2016 This study used qualitative design focusing on the errors made by the second year students of MAN 2 Samarinda. The variable of this study was errors on auxiliary verbs. The variable was measured by using an objective test on auxiliary verbs.
Siti Djulaikah
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source