Results 51 to 60 of about 45,530 (292)

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

O efeito da alternância nos exercícios de grande e pequenos grupamentos em membros inferiores sobre a lactacidemia e parâmetros cardiovasculares

Revista Brasileira de Prescrição e Fisiologia do Exercício, 2017
O objetivo do presente estudo foi verificar a influência na alternância na ordem de execução de exercícios para membros inferiores: Agachamento Livre (AGL) e cadeira extensora (CE) sobre a lactacidemia, escala de percepção de esforço de OMNI e parâmetros
Giovani Veira da Costa, José Campanholi Neto, Autran José Silva Júnior, Vilmar Baldissera   +3 more
doaj  

Circumferential Viscodilation Ab Interno Combined with Phacoemulsification for Treatment of Open-Angle Glaucoma: 12-Month Outcomes

Clinical Ophthalmology, 2020
Nathaniel Tracer,1 Jaime E Dickerson Jr,2,3 Nathan M Radcliffe4 1NYU School of Medicine, New York, NY, USA; 2Sight Sciences, Inc, Menlo Park, CA, USA; 3North Texas Eye Research Institute, UNTHSC, Fort Worth, TX, USA; 4Mt Sinai School of Medicine, New ...
Tracer N, Dickerson JE Jr, Radcliffe NM
doaj  

Analysing 3429 digital supervisory interactions between Community Health Workers in Uganda and Kenya: the development, testing and validation of an open access predictive machine learning web app

Human Resources for Health, 2022
Background Despite the growth in mobile technologies (mHealth) to support Community Health Worker (CHW) supervision, the nature of mHealth-facilitated supervision remains underexplored.
James O’Donovan, Ken Kahn, MacKenzie MacRae, Allan Saul Namanda, Rebecca Hamala, Ken Kabali, Anne Geniets, Alice Lakati, Simon M. Mbae, Niall Winters   +9 more
doaj   +1 more source

Moving to omni-channel retailing : requirements and implementation [PDF]

, 2019
Tämä tutkielma tutkii omni-kanavaisen vähittäiskauppaan siirtymistä, mitä se yritykseltä edellyttää ja miten sitä toteutetaan. Tutkimuksen tavoitteena on selittää, mitä omni-kanavainen liiketoiminta on ja antamaan ohjeistusta sen vaatimista ...
Koskinen, Kalle
core   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source

Design and Development of a Comprehensive Omni directional Soccer Player Robot

International Journal of Advanced Robotic Systems, 2004
Omni directional mobile robots have been popularly employed in several applications especially in soccer player robots considered in Robocup competitions.
Hooman Aghaebrahimi Samani, Amir Abdollahi, Hossein Ostadi, Saeed Ziaee Rad   +3 more
doaj   +1 more source

Adverse maternal and neonatal outcomes among singleton pregnancies in women of very advanced maternal age: a retrospective cohort study

BMC Pregnancy and Childbirth, 2019
Background There is an increasing prevalence of women who tend to delay childbirth until a very advanced age. However, there is sparse data regarding very advanced maternal age (vAMA) and the interplay between vAMA and assisted reproductive technology ...
Yuelin Wu, Yan Chen, Minxue Shen, Yanfang Guo, Shi Wu Wen, Andrea Lanes, Ruth Rennicks White, Adewumi Adanlawo, Mark Walker, Xiaolin Hua   +9 more
doaj   +1 more source