Results 131 to 140 of about 254,235 (292)

Omnibus Study No 2 2000

open access: yes
Themes for Omnibus no 2 2000: - Traveling over the last three months (Section for Transport, tourism and ICT statistics at SSB) - Smoking habits - Voting - Organizational membership - Health issues - Attitudes towards immigrants - Visiting museums The ...
Statistics Norway
core  

m5C Reader ALYREF Promotes the Progression of Endometrial Cancer by Activating the XRCC6‐Mediated Wnt/β‐catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study identifies ALYREF as an oncogenic m5C reader in endometrial cancer. ALYREF recognizes NSUN2‐mediated m5C modification on XRCC6 mRNA to enhance transcript stability and increase XRCC6 expression. Elevated XRCC6 activates Wnt/β‐catenin signaling, resulting in accelerated tumor cell proliferation, migration, invasion, and xenograft tumor growth.
Linlin Hao   +8 more
wiley   +1 more source

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

open access: yesAdvanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu   +13 more
wiley   +1 more source

The Ominous Omnibus [PDF]

open access: yes
The European Commission’s Digital Omnibus proposal to impose additional limits on the right of access to personal data is not a technical clean-up of EU digital law, but a near verbatim reproduction of industry lobbying demands. The proposal restricts the very tool used by citizens, NGOs, journalists, workers, researchers, and civil society to uncover ...
openaire   +1 more source

Interleukin‐1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis

open access: yesAdvanced Science, EarlyView.
During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum   +13 more
wiley   +1 more source

Nante's erste Omnibus-Fahrt in Berlin

open access: yes
NANTE'S ERSTE OMNIBUS-FAHRT IN BERLIN Nante's erste Omnibus-Fahrt in Berlin / Weinholz, Albert Heinrich (Public Domain) ( - ) Illustration ( - ) Title page ( - ) Personen: ( - ) Erste Scene ( - ) Zweite Scene (18 ...
Weinholz, Albert Heinrich
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Other title: Actions Summary

open access: yes, 2006
"May 12, 2006."; The Division of Health Policy and Finance was transferred to the Kansas Health Policy Authority on July 1, 2006.; Summary of the actions taken by the Omnibus Budget Conference Committee concerning the budget requests made by the Kansas ...
Kansas. Department of Administration. Division of Health Policy and Finance.
core  

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

open access: yesAdvanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao   +12 more
wiley   +1 more source

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

open access: yesAdvanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan   +13 more
wiley   +1 more source

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