Results 31 to 40 of about 503,948 (102)

Safety and effectiveness of a somatropin biosimilar in children requiring growth hormone treatment: second analysis of the PATRO Children study Italian cohort [PDF]

, 2020
Purpose: To investigate the long-term safety (primary endpoint) and effectiveness (secondary endpoint) of the somatropin biosimilar Omnitrope®. Methods: PATRO Children is an ongoing, multicenter, observational, post-marketing surveillance study. Children
Greggio N. A., Iughetti, L, Guazzarotti, L, Tornese, G, Gallinari P., Minelli R., Stagi, S, Stagi S., Ragusa L., Perrone L., Antoniazzi F., Persani L., Guazzarotti L., Aversa, T, Giavoli C., Perrone, L, Aversa T., Zecchino, C, Minelli, R, Fedeli, P, Ragusa, L, Zouater, H, Antoniazzi, F, Pozzobon G., Gallinari, P, Greggio, N A, Tornese G., Zucchini S., Bona, G, Iughetti L., Fedeli P., Giavoli, C, Bona G., Persani, L, Pozzobon, G, Zucchini, S, Zecchino C., Zouater H.   +37 more
core   +1 more source

Cancer treatment with biosimilar drugs: A review. [PDF]

Cancer Innov
With crucial mutational categories, biosimilar drug prototypes, and clinical practices including blood and liquid biopsy, cell therapy, gene therapy, recombinant therapeutic proteins, and tailored pharmaceuticals, it aids in targeting certain organs.
Malakar S, Gontor EN, Dugbaye MY, Shah K, Sinha S, Sutaoney P, Chauhan NS.   +6 more
europepmc   +2 more sources

Safety and effectiveness of Omnitrope® in patients with growth hormone deficiency: snapshot analysis of PATRO Adults study in the Italian population

, 2020
Purpose: PATRO adults is an ongoing, multicenter, observational, post-marketing surveillance study aimed at investigating the long-term safety (primary endpoint) and effectiveness (secondary endpoint) of the recombinant human growth hormone (rhGH ...
Gasco V., Puxeddu E., Arnaldi G., Vettor R., Ambrosio M. R., Fedeli P., Arosio M., Gallinari P., Giavoli C., Ferone D., Zouater H.   +10 more
core   +1 more source

Long-term safety and effectiveness of a somatropin biosimilar (Omnitrope®) in children requiring growth hormone therapy: analysis of final data of Italian patients enrolled in the PATRO children study [PDF]

Purpose Omnitrope® (a somatropin biosimilar), used to treat growth disturbances, is considered to have a good safety profile in children. Here, we present the analysis of final data of the Italian cohort of the PAtients TReated with Omnitrope® (PATRO ...
Bellone S, Zabransky M, Zucchini S, Zecchi E, Fedeli P, Giavoli C, Aversa T, Lucaccioni L, Antoniazzi F, Street ME, Miraglia Del Giudice E, Stagi S, Guazzarotti L, Tornese G, Ragusa L, Pozzobon G, Zecchino C, Persani L, Mameli C, Iughetti L   +19 more
core   +3 more sources

Diagnostic value of Xpert® BC Detection, Bladder Epicheck®, Urovysion® FISH and cytology in the detection of upper urinary tract urothelial carcinoma. [PDF]

, 2023
PURPOSE Following the current guidelines, diagnosis and staging for upper urinary tract tumours (UTUC) can be performed with Computed Tomography, urography, ureterorenoscopy (URS) and selective cytology.
Danuser, Hansjörg, Pycha, Armin, Christine Schwienbacher, Hansjörg Danuser, Carolina D’Elia, Hanspeter, Esther, Mian, Christine, D'Elia, Carolina, Esther Hanspeter, Margherita Palermo, Stefan Pycha, Emanuela Trenti, Trenti, Emanuela, Armin Pycha, Schwienbacher, Christine, Pycha, Stefan, Palermo, Margherita, Christine Mian   +17 more
core   +1 more source

Reversal of epigenetic aging and immunosenescent trends in humans

Aging Cell, Volume 18, Issue 6, December 2019., 2019
Epigenetic aging—an accurate measure of biological aging in humans—can run in reverse. A thymus regeneration protocol has enabled estimated biological age to decrease in healthy 51‐ to 65‐year‐old men by 1.5 years after 1 year of treatment (or by 2.5 years compared to chronological age). This significantly exceeds the heretofore theoretical concept of “
Gregory M. Fahy, Robert T. Brooke, James P. Watson, Zinaida Good, Shreyas S. Vasanawala, Holden Maecker, Michael D. Leipold, David T. S. Lin, Michael S. Kobor, Steve Horvath   +9 more
wiley   +1 more source

Comparing the Behavioural Effects of Exogenous Growth Hormone and Melatonin in Young and Old Wistar Rats

Oxidative Medicine and Cellular Longevity, Volume 2016, Issue 1, 2016., 2016
Growth hormone (GH) and melatonin are two hormones with quite different physiological effects. Curiously, their secretion shows parallel and severe age‐related reductions. This has promoted many reports for studying the therapeutic supplementation of both hormones in an attempt to avoid or delay the physical, physiological, and psychological decay ...
Pere Barceló, Cristina Nicolau, Antoni Gamundí, Maria A. Fiol, Jesús A. F. Tresguerres, Mourad Akaârir, Rubén V. Rial, Giuseppe Cirillo   +7 more
wiley   +1 more source

Collecting, archiving and processing DNA from wildlife samples using FTA® databasing paper [PDF]

, 2004
Background Methods involving the analysis of nucleic acids have become widespread in the fields of traditional biology and ecology, however the storage and transport of samples collected in the field to the laboratory in such a manner to allow ...
LA Burgoyne, Smith, L M, LM Smith, Burgoyne, Leigh Alexander   +3 more
core   +1 more source

Biosimilars in Developed and Developing East and Southeast Asian Countries: Japan, South Korea, and Malaysia—Overview, Evolution, and Regulations Assessment

BioMed Research International, Volume 2016, Issue 1, 2016., 2016
The development of biological products has experienced continuous growth over the past three decades. The expiration of patent protection for many biological medicines has led to the development of biosimilars in many countries around the world. This paper reviews the literature on biosimilar drugs and covers their therapeutic status, clinical trials ...
Tomas Gabriel Bas, Carolina Oliu Castillo, Sanjay Garg   +2 more
wiley   +1 more source

Eco-effective fashion theory: how to implement the Cradle to Cradle® concept into fashion and clothing design?: the designer's professional, economic, social and enviromental role [PDF]

, 2013
vaatetussuunnitteluun ja muotiin. Tutkimukseni pyrkii vastaamaan kahteen kysymykseen: 1. Kuinka soveltaa Cradle to Cradle® konsepti vaatesuunnitteluun ja muotiin? 2.
Kupsala, Heta
core   +2 more sources