Results 31 to 40 of about 306 (101)
The Impact of Growth Hormone Therapy on Sleep-Related Health Outcomes in Children with Prader–Willi Syndrome: A Review and Clinical Analysis [PDF]
, 2023 This literature review of growth hormone (GH) therapy and sleep-related health outcomes in children diagnosed with Prader–Willi syndrome (PWS) assembles evidence for the consequences of sleep deprivation and poor sleep quality: difficulty concentrating ...
Alessandra Guzzo +4 more
core +1 more source
Switching From Originator to Biosimilar Human Growth Hormone Using Dialogue Teamwork: Single-Center Experience From Sweden [PDF]
, 2013 INTRODUCTION: A new treatment plan was implemented at Skåne University Hospital, on economic grounds, for children requiring recombinant human growth hormone (rhGH) treatment.
Carl-Erik Flodmark +3 more
core +1 more source
Understanding patient and caregiver perspectives using a dyad approach for data collection: A systematic review of the literature [PDF]
, 2022 Treatments outside of a clinical setting may be managed independently by the pediatric patient, independently by a caregiver, or by the patient and caregiver together.
Lamoureux, Roger +6 more
core +2 more sources
The influence of Arginine and counter-ions: Antibody stability during freeze-drying. [PDF]
, 2021 Amino acids, for example L-arginine, are used in lyophilisation as crystalline bulking, buffering, viscosity reducing or stabilising excipients. In this study, arginine was formulated with different counter ions (hydrochloride, citrate, lactobionate ...
Alessandro Bregolin +3 more
core +1 more source
Risk Management Plan and Pharmacovigilance System. Biopharmaceuticals: Biosimilars [PDF]
, 2011 Editor literario del libro, Giancarlo Nota - All chapters are Open Access articles distributed under the Creative Commons Non Commercial-Share Alike-Attribution 3.0 license, which permits to copy, distribute, transmit, and adapt the work in any medium ...
Calvo, Begoña, Zúñiga, Leyre
core +3 more sources
Reversal of epigenetic aging and immunosenescent trends in humans
Aging Cell, Volume 18, Issue 6, December 2019., 2019 Epigenetic aging—an accurate measure of biological aging in humans—can run in reverse. A thymus regeneration protocol has enabled estimated biological age to decrease in healthy 51‐ to 65‐year‐old men by 1.5 years after 1 year of treatment (or by 2.5 years compared to chronological age). This significantly exceeds the heretofore theoretical concept of “
Gregory M. Fahy +9 more
wiley +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2016, Issue 1, 2016., 2016 Growth hormone (GH) and melatonin are two hormones with quite different physiological effects. Curiously, their secretion shows parallel and severe age‐related reductions. This has promoted many reports for studying the therapeutic supplementation of both hormones in an attempt to avoid or delay the physical, physiological, and psychological decay ...
Pere Barceló +7 more
wiley +1 more source
BioMed Research International, Volume 2016, Issue 1, 2016., 2016 The development of biological products has experienced continuous growth over the past three decades. The expiration of patent protection for many biological medicines has led to the development of biosimilars in many countries around the world. This paper reviews the literature on biosimilar drugs and covers their therapeutic status, clinical trials ...
Tomas Gabriel Bas +2 more
wiley +1 more source
Effect of switching recombinant human growth hormone: Comparative analysis of phase 3 clinical data [PDF]
, 2011 INTRODUCTION: Recombinant human growth hormone (rhGH) is effective and safe when used to treat growth hormone deficiency (GHD) in children. However, it has been suggested that switching between different types of rhGH can have a detrimental effect on ...
Markus Zabransky +4 more
core +1 more source
Host Cell Protein Clinical Safety Risk Assessment—An Updated Industry Review
Biotechnology and Bioengineering, Volume 122, Issue 11, Page 3229-3248, November 2025.ABSTRACT Host cell proteins (HCP) are process‐related impurities that can co‐purify with therapeutic proteins. Some HCP impurities potentially can have an impact on patient safety (immunogenicity or toxicity), efficacy, and/or product quality. It is important to reduce the levels of HCP impurities with a well‐controlled manufacturing process and to ...
Lisette Coye +19 more
wiley +1 more source