Results 61 to 70 of about 1,576 (169)

Analysis of Retinal Thickness in Patients With Chronic Diseases Using Standardized Optical Coherence Tomography Data: Database Study Based on the Radiology Common Data Model

JMIR Medical Informatics
BackgroundThe Observational Medical Outcome Partners-Common Data Model (OMOP-CDM) is an international standard for harmonizing electronic medical record (EMR) data.
ChulHyoung Park, So Hee Lee, Da Yun Lee, Seoyoon Choi, Seng Chan You, Ja Young Jeon, Sang Jun Park, Rae Woong Park   +7 more
doaj   +1 more source

Medical Data as a Key Asset in the Digital Health Era: A Framework for Challenges and Strategies

iMetaMed, Volume 1, Issue 2, December 2025.
By conducting case studies and comparative analysis from a global perspective, this study develops the practical framework of Medical Data Element Ecosystem (MDEE)—one that facilitates MDEE construction by guiding actions, informing policy‐making, and enabling stakeholder engagement.
Jian Wang, Anqi Lin, Yedong Huang, Gezheng Li, Tianqi Chen, Chudi Sun, Weiye Qian, Shiqi Ren, Hank Z. H. Wong, Yanxi Ding, Lin Zhang   +10 more
wiley   +1 more source

Conceptual design of a generic data harmonization process for OMOP common data model

BMC Medical Informatics and Decision Making
Background To gain insight into the real-life care of patients in the healthcare system, data from hospital information systems and insurance systems are required. Consequently, linking clinical data with claims data is necessary.
Elisa Henke, Michele Zoch, Yuan Peng, Ines Reinecke, Martin Sedlmayr, Franziska Bathelt   +5 more
doaj   +1 more source

Implementing a Common Data Model in Ophthalmology: Mapping Structured Electronic Health Record Ophthalmic Examination Data to Standard Vocabularies

Ophthalmology Science
Objective: To identify and characterize concept coverage gaps of ophthalmology examination data elements within the Cerner Millennium electronic health record (EHR) implementations by the Observational Health Data Sciences and Informatics Observational ...
Justin C. Quon, MD, Christopher P. Long, MD, William Halfpenny, MBBS, MEng, Amy Chuang, MS, Cindy X. Cai, MD, MS, Sally L. Baxter, MD, MSc, Vamsi Daketi, MS, Amanda Schmitz, BS, Neil Bahroos, MS, Benjamin Y. Xu, MD, PhD, Brian C. Toy, MD   +10 more
doaj   +1 more source

An Ontology-Based Approach for Consolidating Patient Data Standardized With European Norm/International Organization for Standardization 13606 (EN/ISO 13606) Into Joint Observational Medical Outcomes Partnership (OMOP) Repositories: Description of a Methodology

JMIR Medical Informatics, 2023
BackgroundTo discover new knowledge from data, they must be correct and in a consistent format. OntoCR, a clinical repository developed at Hospital Clínic de Barcelona, uses ontologies to represent clinical knowledge and map ...
Santiago Frid, Xavier Pastor Duran, Guillem Bracons Cucó, Miguel Pedrera-Jiménez, Pablo Serrano-Balazote, Adolfo Muñoz Carrero, Raimundo Lozano-Rubí   +6 more
doaj   +1 more source

OMOP-on-FHIR: Integrating the Clinical Data Through FHIR Bundle to OMOP CDM

The harmonization of the OMOP Common Data Model (CDM) with HL7 FHIR aims to enhance interoperability in clinical research by harmonizing diverse healthcare datasets. This process, referred to as OMOP-on-FHIR, leverages FHIR Bundles for real-time clinical data exchange and transforms these resources into OMOP CDM format using an ETL process.
Jayathissa, Prabath, Rohatsch, Lukas, Sauermann, Stefan, Hussein, Rada   +3 more
openaire   +2 more sources

Key Stakeholders' Knowledge, Opinions, and Interests on Real‐World Evidence in the Regulatory Process—Results of an EU‐Wide Survey

Clinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Real‐world data (RWD) and real‐world evidence (RWE) are increasingly gaining attention in supporting drug regulatory decision making. This study assessed knowledge, opinions, and usage patterns of key stakeholders regarding the status of RWD/RWE and AI implementation in health technology assessment (HTA) and drug regulation and aimed to ...
Frank Lucas Depner, Martin Russek, Christoph Röthlein, Cornelia Becker, Jonas Peltner, Kerstin Pfeifer, Evy Reviers, Dirk De Valck, Julia Wicherski, Sirpa Hartikainen, Anna‐Maija Tolppanen, Britta Haenisch   +11 more
wiley   +1 more source

Baseline characteristics of atopic eczema patients enrolled in seven European registries united in the TREatment of ATopic eczema (TREAT) registry taskforce

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 12, Page 2096-2112, December 2025.
This pooled analysis of 5337 atopic eczema patients from seven TREAT registries shows variability and consistency in data collection, provides key baseline insights and demonstrates the feasibility of harmonized real‐world data. It lays the foundation for future TREAT Taskforce studies on treatment outcomes, supporting cross‐border research to guide ...
A. H. Musters, L. A. A. Gerbens, L. van der Gang, M. A. Middelkamp‐Hup, W. Ouwerkerk, D. J. Hijnen, E. Haufe, L. Heinrich, T. Werfel, S. Weidinger, J. Schmitt, A. Svedbom, E. K. Johansson, M. Bradley, L. B. von Kobyletzki, I. Vittrup, I. F. Ruge, J. P. Thyssen, C. Vestergaard, J. M. Carrascosa, M. de Vega, I. García‐Doval, A. Chiricozzi, L. Stingeni, P. Calzavara‐Pinton, M. R. Ardern‐Jones, N. J. Reynolds, C. Flohr, P. I. Spuls, on behalf of the A‐STAR, AtopyReg, BIOBADATOP, SCRATCH, SwedAD, TREATgermany and TREAT NL/BE registry teams, Angela Bosma, Anouk Caron, Ariënna Hyseni, Jitske Dijkstra, Ly Nguyen, Sofie De Schepper, Hilde Lapeere, David De Waele, Paula Beattie, Sara Brown, Tim Burton, John Ingram, Alan Irvine, Graham Johnston, Irene Man, Andrea Manca, Graham Ogg, Thomas Patton, Mandy Wan, Richard Warren, Richard Woolf, Manisha Baden, David Prieto‐Merino, Rayka Malik, Bola Coker, Lilia De La Cruz, Elizaveta Gribaleva, Tanzeem Begum, Miguel Angel Descalzo, Ángeles Flórez, Ana María Giménez Arnau, Alicia González Quesada, Juan Francisco Silvestre, Mercedes Rodríguez Serna, Pablo Chicharro, Yolanda Gilaberte, Pablo de la Cueva, Trini Montero, Marta Elosua González, Ricardo Ruiz Villaverde, José Juan Pereyra Rodríguez, Ana Batalla Cebey, Martina Espasandin Arias, Carmen Couselo Rodríguez, Laia Curto, Marta Bertolín, Irene Castaño, Isabel Betlloch, Miguel Antonio Lasheras Pérez, Javier Abilio Sánchez Pérez, Adrián Ballano Ruiz, Mónica Munera, Salvador Arias‐Santiago, Gastón Roustan, Raquel Sanabria de la Torre, Angel Rosell Diaz, José Carlos Ruiz Carrascosa, Francisco J. Navarro Triviño, Jesper Elberling, Lone Skov, Kristina Ibler, Gregor Jemec, Charlotte Möertz, Carsten Bindslev‐Jensen, Maria Kamstrup, Alexander Egeberg, Mette Deleuran, Mikael Alsterholm, Chris D. Anderson, Maria Bradley, Lena Holm Sommar, Lina Ivert, Emma K. Johansson, Anna Josefson, Lena Lundeberg, Maria Lundqvist, Elisabet Nylander, MariHelen Sandström‐Falk, Alexander Shayesteh, Gunnthorunn Sigurdardottir, Andreas Sonesson, Axel Svedbom, Åke Svensson, Marie Virtanen, Laura von Kobyletzki, Sophie Vrang, Carl‐Fredrik Wahlgren, Monica Corazza, Maria Esposito, Gabriella Fabbrocini, Maria Concetta Fargnoli, Silvia M. Ferrucci, Caterina Foti, Giampiero Girolomoni, Katharina Hansel, Angelo V. Marzano, Maddalena Napolitano, Maria Passante, Cataldo Patruno, Ketty Peris, Paolo Daniele Pigatto, Marco Romanelli, Paolo Romita, Mariateresa Rossi, Donatella Schena, Natale Schettini, Giulia Tonini   +141 more
wiley   +1 more source

Comparative Risk for Neuropsychiatric Events in Leukotriene Receptor Antagonist vs. Inhaled Corticosteroid in Children With Asthma: A Nationwide Observational Study With a Complementary Analysis Using Natural Language Processing

Pharmacoepidemiology and Drug Safety, Volume 34, Issue 11, November 2025.
ABSTRACT Purpose Leukotriene receptor antagonists (LTRAs) are widely prescribed as controller medications for pediatric asthma. However, there have been increasing concerns about potential neuropsychiatric adverse reactions associated with LTRAs.
Subin Kim, Chang Hoon Han, Junhyuk Chang, Jaehyeong Cho, Kyunguk Jeong, Hamin Kim, Mireu Park, Soo Yeon Kim, Jong Deok Kim, Myung Hyun Sohn, Sooyoung Lee, Rae Woong Park, Seng Chan You, Kyung Won Kim   +13 more
wiley   +1 more source

Integrating longitudinal mental health data into a staging database: harnessing DDI-lifecycle and OMOP vocabularies within the INSPIRE Network Datahub

Frontiers in Big Data
BackgroundLongitudinal studies are essential for understanding the progression of mental health disorders over time, but combining data collected through different methods to assess conditions like depression, anxiety, and psychosis presents significant ...
Bylhah Mugotitsa, Bylhah Mugotitsa, Tathagata Bhattacharjee, Michael Ochola, Dorothy Mailosi, David Amadi, Pauline Andeso, Joseph Kuria, Reinpeter Momanyi, Evans Omondi, Evans Omondi, Dan Kajungu, Jim Todd, Agnes Kiragga, Agnes Kiragga, Jay Greenfield   +15 more
doaj   +1 more source