Results 81 to 90 of about 10,092 (247)

Ontogenetic Development of Hyperostosis in the Crevalle Jack Caranx hippos (Linnaeus, 1766) and New Records of Affected Bone Regions

Journal of Fish Diseases, EarlyView.
ABSTRACT Hyperostosis is a non‐pathological condition widely reported in marine teleosts, yet its developmental dynamics and underlying drivers remain poorly understood. This study investigates the ontogenetic progression and anatomical distribution of hyperostosis in Caranx hippos based on a growth series of 39 specimens collected along the Brazilian ...
Camila Vitória Gonçalves Ferreira, Davi Lettieri Santos dos Abrahão, Alice Miranda Cardoso de‐Sá, Alice Barbosa Henriques, Ana Julia Araujo Rosa D’ Almeida Lima, Maykon Victor Rezende de Oliveira, Márcia Carolina Salomão, Helena Passeri Lavrado, Fernando Augusto Pereira Tuna   +8 more
wiley   +1 more source

Assessment of Cannabidiol Supplements Use in Small Animals Practice in Portugal

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study aimed to assess the current use of cannabidiol supplements (CBDS) by Portuguese small animal veterinary practitioners. An anonymous online survey questioning the frequency of CBDS use, purpose of use and the perceived outcome was developed using Microsoft Forms, and targeted veterinarians currently working in small animal clinics in
Maria Inês Santos, Ana Luísa Lourenço
wiley   +1 more source

Periplasmic crowding and peptidoglycan hydrolase activity as drivers of outer membrane vesiculation in Acinetobacter baumannii

Communications Biology
Acinetobacter baumannii produces outer membrane vesicles (OMVs) to alleviate envelope stress, though the mechanisms remain poorly understood. To induce periplasmic accumulation of misfolded proteins and trigger stress, a degP mutant is exposed to ...
Bitnara Kim, Yongjun Son, Reagan Lee, Jihyeon Min, Woojun Park   +4 more
doaj   +1 more source

Peptidylarginine Deiminase Inhibitors Reduce Bacterial Membrane Vesicle Release and Sensitize Bacteria to Antibiotic Treatment

Frontiers in Cellular and Infection Microbiology, 2019
Outer membrane and membrane vesicles (OMV/MV) are released from bacteria and participate in cell communication, biofilm formation and host-pathogen interactions. Peptidylarginine deiminases (PADs) are phylogenetically conserved enzymes that catalyze post-
Uchini S. Kosgodage, Paul Matewele, Giulia Mastroianni, Igor Kraev, Dominik Brotherton, Brigitte Awamaria, Anthony P. Nicholas, Sigrun Lange, Jameel M. Inal   +8 more
doaj   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Significances of OMV and Extracellular Vesicle Proteomics

Journal of Data Mining in Genomics & Proteomics, 2017
Outer Membrane Vesicle (OMV) proteome has been involved into the pathogenesis of diseases and resistance of microorganisms against a number of antibiotics, mechanism of action of probiotics and host-pathogen interaction etc. We have enlightened the role played by extracellular vesicles proteomics in the pathogenesis of different diseases ...
openaire   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Subcellular localization of 66 PAO1 OMV core proteins.

, 2019
Subcellular localization of 66 PAO1 OMV core proteins.
Bruce A. Stanton (226728), Angelyca A. Jackson (3837772), Deborah A. Hogan (182962), Katja Koeppen (226723), Roxanna Barnaby (745823), Scott A. Gerber (212370)   +5 more
core   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Isolation of human monoclonal antibodies from 4CMenB vaccinees reveals PorB and LOS as the main OMV components inducing cross-strain protection

Frontiers in Immunology
IntroductionThe 4CMenB vaccine licensed against serogroup B Neisseria meningitidis (MenB) contains three recombinant proteins and Outer Membrane Vesicles (OMV) from a New Zealand epidemic strain. The protective response mediated on differentmeningococcal
Giacomo Vezzani, Giacomo Vezzani, Viola Viviani, Martina Audagnotto, Alessandro Rossi, Paolo Cinelli, Nicola Pacchiani, Chiara Limongi, Laura Santini, Fabiola Giusti, Sara Tomei, Giulia Torricelli, Elisa Faenzi, Chiara Sammicheli, Simona Tavarini, Adriana Efron, Alessia Biolchi, Oretta Finco, Isabel Delany, Elisabetta Frigimelica   +19 more
doaj   +1 more source