Results 31 to 40 of about 72,189,252 (249)

Lower lip as a photoacoustic imaging window for detection of CTC clusters: A feasibility phantom study

Photoacoustics
Detection and continuous monitoring of circulating tumor cells (CTCs) using photoacoustic imaging remains challenging because of weak transient signals and strong blood-background absorption.
Ashkan Ghanbarzadeh-Dagheyan, Elahe Rastegar Pashaki, Kirsten Pondman   +2 more
doaj   +1 more source

On-chip perivascular niche supporting stemness of patient-derived glioma cells in a serum-free, flowable culture [PDF]

, 2021
Glioblastoma multiforme (GBM) is the most common and the most aggressive type of primary brain malignancy. Glioblastoma stem-like cells (GSCs) can migrate in vascular niches within or away from the tumour mass, increasing tumour resistance to treatments ...
Gerigk, M, Gerigk, M., Shi, H.H., Bulstrode, H., Rowitch, D, Bulstrode, H, Shi, HH, Tönisen, F., Huang, Y.Y.S., Morrison, G, Cerutti, C, Tönisen, F, Cerutti, C., Morrison, G., Rowitch, D., Huang, YYS, Harry Bulstrode, Felix Tönisen, Magda Gerigk, Gillian Morrison, David Rowitch, Camilla Cerutti, HaoTian Harvey Shi, Yan Yan Shery Huang   +23 more
core   +1 more source

Miniaturized lensless microfluidic on-chip bio-imaging detection

物联网学报, 2019
The conventional high-resolution optical microscopy for biomedical imaging has high cost and low portability due to bulky optical lenses system.To realize miniaturized imaging,the recent advance of lensless microfluidic on-chip imaging technique based on
Jin CHEN, Xiwei HUANG, Yangbo LI, Jixuan LIU, Lingling SUN   +4 more
doaj   +2 more sources

Multiplexed imaging and effluent analysis to monitor cancer cell intravasation using a colorectal cancer-on-chip

STAR Protocols, 2021
Summary: Despite colorectal cancer’s (CRC) prevalence, its progression is not well understood. The microfluidic organ-on-chip (OOC) model described herein recreates the epithelial-endothelial tissue-tissue interface, fluid flow, and mechanical forces ...
Carly Strelez, Kimya Ghaffarian, Shannon M. Mumenthaler   +2 more
doaj   +1 more source

Imaging based optofluidic interferometer on a chip

, 2010
We introduce for the first time an integrated optofluidic interferometer on a PDMS microfluidic chip. By imaging the local interference patterns inside the chip, both of the fluid pressure and flow rate can be measured.
Psaltis, Demetri, Song, Wuzhou, Wuzhou Song, Demetri Psaltis   +3 more
core   +1 more source

Portable optical microscope-on-a-chip

, 2006
In this paper, we present a novel high resolution optical imaging device on chip. It is based on a line of nano holes defined in an optically opaque aluminum film on a CMOS imaging sensor chip.
Cui, X., Psaltis, D., Erickson, D., Yang, C., Heng, X., Changhuei Yang, Xin Heng, Xiquan Cui, David Erickson, Demetri Psaltis   +9 more
core   +1 more source

Microfluidic Protein Imaging Platform: Study of Tau Protein Aggregation and Alzheimer’s Drug Response

Bioengineering, 2020
Tau protein aggregation is identified as one of the key phenomena associated with the onset and progression of Alzheimer’s disease. In the present study, we performed on-chip confocal imaging of tau protein aggregation and tau–drug interactions using a ...
Shubha Jain, Sarpras Swain, Lopamudra Das, Sarita Swain, Lopamudra Giri, Anand Kumar Kondapi, Harikrishnan Narayanan Unni   +6 more
doaj   +1 more source

New bioimaging avenues for organs‐on‐chips by integration of bioluminescence

View, 2021
The unmet demand for the development of advanced in vitro models that emulate key features of human (patho‐)physiology and organ or tissue functionality led to the emergence of organ‐on‐a‐chip screening platforms.
Liliana Moreira Teixeira, Laura Mezzanotte   +1 more
doaj   +1 more source

Advancements in Spaceborne Synthetic Aperture Radar Imaging with System-on-Chip Architecture and System Fault-Tolerant Technology

Remote Sensing, 2023
With the continuous development of satellite payload and system-on-chip (SoC) technology, spaceborne real-time synthetic aperture radar (SAR) imaging systems play a crucial role in various defense and civilian domains, including Earth remote sensing ...
Yu Xie, Yizhuang Xie, Bingyi Li, He Chen
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source