Results 51 to 60 of about 72,189,252 (249)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)

open access: yes, 2020
We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing
Campos, C. D. M.   +5 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Broadband on-chip spectral sensing via directly integrated narrowband plasmonic filters for computational multispectral imaging

open access: yesNanophotonics
Spectroscopy underpins a wide range of applications, including biomedical diagnostics, precision agriculture, remote sensing, and industrial process control.
Zheng Qilin   +8 more
doaj   +1 more source

A Concept for a Sensitive Micro Total Analysis System for High Throughput Fluorescence Imaging

open access: yesSensors, 2006
This paper discusses possible methods for on-chip fluorescent imaging forintegrated bio-sensors. The integration of optical and electro-optical accessories, accordingto suggested methods, can improve the performance of fluorescence imaging.
Yosi Shacham, Arthur Rabner
doaj   +1 more source

Multi-Scale Histogram-Based Probabilistic Deep Neural Network for Super-Resolution 3D LiDAR Imaging

open access: yesSensors, 2022
LiDAR (Light Detection and Ranging) imaging based on SPAD (Single-Photon Avalanche Diode) technology suffers from severe area penalty for large on-chip histogram peak detection circuits required by the high precision of measured depth values.
Miao Sun   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Correction: 3D printed nervous system on a chip

open access: yes, 2016
Correction for ‘3D printed nervous system on a chip’ by Blake N.
Meng, Fanben   +6 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Instant ghost imaging: algorithm and on-chip implementation

open access: yesOptics Express, 2020
Ghost imaging (GI) is an imaging technique that uses the correlation between two light beams to reconstruct the image of an object. Conventional GI algorithms require large memory space to store the measured data and perform complicated offline calculations, limiting practical applications of GI. Here we develop an instant ghost imaging (IGI) technique
Zhe Yang   +4 more
openaire   +3 more sources

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