Results 61 to 70 of about 72,189,252 (249)

Image-based navigation on a chip [PDF]

open access: yesProceedings of the 21st IEEE Instrumentation and Measurement Technology Conference (IEEE Cat. No.04CH37510), 2004
In semiconductor industry, where highest levels of precision and robustness are required, machine vision tools evolved to become a mainstream automation tools that guide robotic handling, assembly and inspection processes. This paper presents an algorithm for navigation on a chip that is based on localization of microscopic eye-point images using a ...
M. Lifshits, E. Rivlin, M. Rudzsky
openaire   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Bone-on-a-Chip Systems for Hematological Cancers

open access: yesBiosensors
Hematological malignancies originating from blood, bone marrow, and lymph nodes include leukemia, lymphoma, and myeloma, which necessitate the use of a distinct chemotherapeutic approach.
Gül Kozalak, Ali Koşar
doaj   +1 more source

On-Chip Compressive Sensing with a Single-Photon Avalanche Diode Array

open access: yesSensors, 2023
Single-photon avalanche diodes (SPADs) are novel image sensors that record photons at extremely high sensitivity. To reduce both the required sensor area for readout circuits and the data throughput for SPAD array, in this paper, we propose a snapshot ...
Chenxi Qiu   +6 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Recent Advancements in Fish-on-Chip: A Comprehensive Review

open access: yesFluids
Zebrafish (Danio rerio) emerged as a suitable vertebrate model organism in the 1960s, owing to its transparent embryos and ease of breeding. Research utilizing zebrafish as a model organism gained significant momentum in the 1970s, particularly in the ...
Tushar Nath, Hua Tan
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

On-chip label-free plasmonic based imaging microscopy for microfluidics

open access: yes, 2018
In this work, we demonstrated on-chip label-free imaging microscopy using real and Fourier Plane (FP) microscopic dark field images of Surface Plasmons (SP), excited on engineered 1D and 2D low aspect ratio periodic plasmonic nanostructures. The periodic
P. Arora (7611206)   +1 more
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Breakthroughs in Photonics 2013: Holographic Imaging

open access: yesIEEE Photonics Journal, 2014
Although holography is topic that goes back to the 1950s, the research in this field continues to be very active worldwide. A continuous growth is confirmed by the publication of more than 2000 papers each year in archival journal on different ...
P. Memmolo   +5 more
doaj   +1 more source

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