Results 41 to 50 of about 49,609,782 (317)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

User oriented access to secure biomedical resources through the grid [PDF]

, 2006
The life science domain is typified by heterogeneous data sets that are evolving at an exponential rate. Numerous post-genomic databases and areas of post-genomic life science research have been established and are being actively explored. Whilst many of
Watt, J, Ajayi, O, Jiang, J, Ajayi, O., Sinnott, R, Jiang, J., Sinnott, R.O., Stell, A, Stell, A.J., Watt, J.   +9 more
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Environmental data set for the design and analysis of the Photovoltaic system in the Jordan Valley

Data in Brief, 2020
Renewable energy penetration in the national electrical grid in Jordan has been rapidly increasing in the last few years, touching nearly 30%. Limited grid capacity has been a driver to slow down large-scale projects and has motivated increased attention
Zakariya Dalala, Mohammad Al-Addous, Firas Alawneh, Christina B. Class   +3 more
doaj   +1 more source

Design and Implementation of a Solar Power System on Grid SDN 023905 BIN JAI using PVSYST Software

Majlesi Journal of Electrical Engineering, 2023
Electricity is an indispensable requirement for modern society, and with the advancement of technology, the adoption of renewable energy sources, such as Solar Power Plants (PLTS), has been on the rise.
Raihan Putri, Asri Asri, Rosdiana Rosdiana, Fakhruddin Ahmad Nasution, Wahyu Pujianto Trinanda   +4 more
doaj   +1 more source

Scintillating Grid Illusion Without the Grid [PDF]

i-Perception, 2020
The scintillating grid illusion is a phenomenon where illusory black spots are perceived on white patches located at the intersections of a grid pattern. In this study, I report that the illusory spots as observed in the illusion are perceived with a stimulus pattern without grid bars. In two experiments, I investigated the perceptual properties of the
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Grid Characteristics and Uses: A Grid Definition [PDF]

, 2004
This paper discusses the concept of grid towards achieving a complete definition using main grid characteristics and uses found in literature. Ten definitions extracted from main literature sources have been studied allowing the extraction of grid characteristics while grid uses are defined in terms of the different types of application support ...
Miguel L. Bote-Lorenzo, Yannis A. Dimitriadis, Eduardo Gómez-Sánchez   +2 more
openaire   +1 more source

The Collaborative Semantic Grid

, 2006
Grid and Semantic Web technologies both enable heterogeneous resources to be joined up to achieve new functionality and capability, and their combined effectiveness has been demonstrated through a number of ‘Semantic Grid’ projects. These typically apply
De Roure, David, Michaelides, Danius, Page, Kevin, Frey, Jeremey, Page, KR, Roure, DD, Frey, JG, Michaelides, DT   +7 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source