Results 131 to 140 of about 3,234,483 (284)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

On-line Monitoring and Analysis of Urban Rail Transit Stray Current

Chengshi guidao jiaotong yanjiu
Objective To ensure the safe operation of underground gas pipeline network near URT (urban rail transit) and to mitigate the electrochemical corrosion on the gas pipeline network caused by URT stray current, it is necessary to conduct online monitoring ...
YANG Guoqing, MA Xuehui
doaj   +1 more source

On-Line Monitoring of Radiocarbon Emissions in a Nuclear Facility with Cavity Ring-Down Spectroscopy. [PDF]

Anal Chem, 2021
Lehmuskoski J, Vasama H, Hämäläinen J, Hokkinen J, Kärkelä T, Heiskanen K, Reinikainen M, Rautio S, Hirvelä M, Genoud G.   +9 more
europepmc   +1 more source

Measurement uncertainty in on-line bushing monitoring

Journal of Energy - Energija
The high voltage bushing on-line monitoring has been performed for many years to prevent unexpected rapid power network failures. Network unbalance correction, based on separate voltage phase measurement or phasor technique, effectively improves the measurements of bushing dielectric dissipation factor tgδ and capacitance factor C1.
Gil, Wiesław, Masłowski, Wiktor
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Bench Testing of Sensors Utilized for In-Line Monitoring of Lubricants and Hydraulic Fluids Properties. [PDF]

Sensors (Basel), 2021
Pochi D, Grilli R, Fornaciari L, Betto M, Benigni S, Fanigliulo R.   +5 more
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

In-line monitoring of surfactant clearance in viral vaccine downstream processing. [PDF]

Comput Struct Biotechnol J, 2021
Payne J, Cronin J, Haer M, Krouse J, Prosperi W, Drolet-Vives K, Lieve M, Soika M, Balmer M, Kirkitadze M.   +9 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Electroluminescent Sensing Coating for On-Line Detection of Zero-Value Insulators in High-Voltage Systems

Applied Sciences
In high-voltage transmission lines, insulators subjected to prolonged electromechanical stress are prone to zero-value defects, leading to insulation failure and posing significant risks to power grid reliability.
Yongjie Nie, Yihang Jiang, Pengju Wang, Daoyuan Chen, Yongsen Han, Jialiang Song, Yuanwei Zhu, Shengtao Li   +7 more
doaj   +1 more source