Results 131 to 140 of about 51,151,627 (314)

Final report on supplementary comparison EURAMET.EM-S32: Comparison of resistance standards at 1 TΩ and 100 TΩ

, 2013
Resistance standards with values in the TΩ range play an important role in electrical instrumentation. The calibration of such standards is, thus, a service offered by many metrology institutes.
Chrobok P, Rietveld R, GALLIANA, FLAVIO, Nicolas J, Godinho I, Raso F, Orzepowski M, Beek J, udek e, Tenev A, Flouda I, Cirneanu L, Gunnarsson O, Lindic M, Jeckelmann B, Vrabcek P., CAPRA, PIER PAOLO, Iisakka I, Snopek L, Erkan O, Istrate D, Schumacher B, Pezel A   +22 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Development of immunogold test strips for chilli veinal mottle virus detection using monoclonal antibodies against the CP

Frontiers in Microbiology
Chilli veinal mottle virus (ChiVMV), a member of the Potyviridae family, a major threat to solanaceous crops, including tobacco and peppers, in China, where it causes systemic necrosis, leaf mottling, and significant yield losses.
Fang Wang, Fang Wang, Chuantao Xu, Ying Chen, Ying Chen, Ke Wang, Xueying An, Xueying An, Benguo Zhou   +8 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Characterization of the resistance mechanism against BYDV-PAV in maize

Frontiers in Agronomy
Arthropods threaten crop production by feeding on plants and, most importantly, by transmitting viruses. BYDV-PAV is the most prevalent virus species that causes barley yellow dwarf disease, one of the most economically important viral diseases affecting
Maria Schmidt, Torsten Will, Britta Ruckwied, Antje Habekuß, Benjamin Stich, Benjamin Stich, Benjamin Stich   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Progress towards implementation of a public health action plan to combat antimicrobial resistance

Since 2002, the Interagency Task Force on Antimicrobial Resistance has released an annual report on the progress towards implementation of the 2001 Action Plan to Combat Antimicrobial Resistance.

core  

Australian Group on Antimicrobial Resistance (AGAR) Australian Gram-negative Sepsis Outcome Programme (GNSOP) Annual Report 2017 [PDF]

, 2019
The Australian Group on Antimicrobial Resistance (AGAR) performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric Gram-negative pathogens.
Bell, J.M. for the Australian Group on Antimicrobial Resistance, Gottlieb, T., Coombs, G.W. (Eds), Daley, D.A.   +3 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source