Results 141 to 150 of about 51,151,627 (314)

The Australian Group on Antimicrobial Resistance(AGAR)

, 2019
The Australian Group on Antimicrobial Resistance (AGAR) is a collaboration of clinicians and scientists working in diagnostic medical microbiology laboratories located across Australia.
Kalukottege, Pankaja, Bradbury, Susan, McLeod, James, Johnson, Paul, Meyer, Ian, Korman, Tony, Hurren, Frances, Robertson, Graham, Winney, Ian, Bernhard, Rose, Gottlieb, Thomas, Branley, James, Givney, Rod, Binotto, Enzo, Thomsett, Bronwyn, Bell, Jan, Coombs, Geoffrey, Kotsanas, Despina, Spelman, Denis, Wilcox, Kathy, Perera, Shalinie, Nourse, Clare, Daley, Denise, Wallace, Janet, Douglass, Linda, Collignon, Peter, Nimmo, Graeme, et al.   +27 more
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CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Effect on oxides on surface topography and thermal contact resistance [PDF]

, 1979
The effect of oxides on the topographies of various random engineering surfaces and steady-state thermal contact resistances between oxidefree and oxidized metallic surfaces in contact in high vacua have been investigated. The results of many previous
Mian, M. N.
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Resistance of a compartmented surface-effect ship

, 2010
A series of carefully controlled experiments on the resistance of a model of a compartmented surface-effect ship has been conducted in a towing tank. Configurations of the model included cases encompassing one subcushion and two subcushions, as well as ...
Day, Alexander, Clelland, David, Beveridge, Philip, Doctors, Lawrence   +3 more
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Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

2006 annual report on progress on \ue2\u20ac\u153A Public Health Action Plan to Combat Antimicrobial Resistance\ue2\u20ac? : executive summary

Surveillance is the ongoing, systematic collection, analysis, and interpretation of data essential to the planning, implementation, and evaluation of public health practice.

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Experimental evolution of herbicide resistance in chlamydomonas reinhardtii [PDF]

Our understanding of the evolutionary dynamics of selection for herbicide resistance is limited by the time and space required to conduct meaningful selection experiments in higher plants. This constrains the study of the
Lagator, Mato
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