Results 171 to 180 of about 51,167,879 (314)

Systematic review and meta-analysis of insecticide resistance status and mechanisms in the arbovirus vector Aedes aegypti from Nigeria. [PDF]

PLoS Negl Trop Dis
Mohammed AK, Dangambo MA, Muhammad A, Alhassan AJ.   +3 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

blaOXA−51-Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in Peru

Journal of Tropical Medicine
Rosario Oporto-Llerena, Rosario Huerto-Huánuco, Yaneth Quispe-Hualpa, Luciano A. Palomino-Kobayashi, Gabriela Soza, Jesús Rojas-Jaimes, Patricia Gonzales, Luis Pollack, Andrea C. Gomez, Gina Salvador-Luján, Edwin Cuaresma, Nestor Luque, Martín Casapia, Kovy Arteaga-Livias, Yolanda Sáenz, Maria J. Pons, Joaquim Ruiz   +16 more
doaj   +1 more source

Disarming Multidrug-Resistant Pathogens: Sodium Dodecyl Sulfate-Induced Plasmid Curing for the Reversal of Resistance and Virulence in <i>Escherichia coli</i>. [PDF]

Int J Microbiol
Eliwa AI, Nassar HSM, Eldahshan MM.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Assessment of Anthelmintic Resistance in Major Gastrointestinal Nematodes in Sheep and Goat Farms in Mymensingh, Bangladesh. [PDF]

J Parasitol Res
Islam MR, Mizan MMH, Anisuzzaman, Khatun MS, Ashad FA, Alam MZ, Roy BC, Dey AR.   +7 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Antibiotic resistance in Canada and the Canadian Committee on Antibiotic Resistance

Canadian Journal of Infectious Diseases, 2000
John Conly
doaj   +1 more source

A Comparison of the Effects of the Timing of Resistance Exercise on Glucose Levels Within the Target Range in People With Type 1 Diabetes (TREX Study): A Randomized Crossover Trial. [PDF]

Diabetes Metab Res Rev
Al Ozairi ES, Hamdan YG, Al Awadhi AA, Al Otaibi NB, Baqer AH, West DJ, Taliping DR, Al Kandari JA, Gray SR.   +8 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source