Results 181 to 190 of about 4,573,504 (288)

Multi-site bone marrow core biopsy improves diagnostic accuracy in dogs with hematologic disease. [PDF]

PLoS One
Smiley KM, Connolly SL, Raskin R, Rosser MF, Schnelle AN, Lopez-Villalobos N, Gal A.   +6 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Scope of Microbial Transglutaminase for Site-Specific and Oriented Immobilization of Native Antibodies from Various Host Species. [PDF]

Langmuir
Beitello E, Osei K, Breausche FE, Friesen JA, Driskell JD.   +4 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Enhancing the Outcome of Crystallographic Fragment Screening by Choosing the Optimal Protein Crystal Form. [PDF]

Small Sci
Barthel T, Wollenhaupt J, Benz LS, Reinke P, Zhang L, Oelker M, Lennartz F, Taberman H, Mueller U, Meents A, Hilgenfeld R, Weiss MS.   +11 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Lower Respiratory Tract Infections: Treatment Challenges and New Therapeutic Options

Canadian Journal of Infectious Diseases, 1998
Lionel Mandell
doaj   +1 more source

Multidisciplinary rehabilitation network enhances outcomes after nerve transfer in brachial plexus birth injury. [PDF]

Childs Nerv Syst
Friedman AJ, Robbins V, Gotlieb-Horowitz M, Behbahani M, Durham S, Meisel E, Koehler SM.   +6 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Cross-site quantitative MRI harmonization: The impact on age modeling in health and disease. [PDF]

Imaging Neurosci (Camb)
Chen X, Ocampo-Pineda M, Lu PJ, Ekerdt C, Weigel M, Jansen MG, Cagol A, Chan KS, Schädelin S, Zwiers M, Oosterman JM, Norris DG, Bayer JMM, Marquand AF, Menks WM, Kuhle J, Kappos L, Melie-Garcia L, Granziera C, Marques JP.   +19 more
europepmc   +1 more source