Results 51 to 60 of about 154,218 (242)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Geomorphological Insights on Human-Volcano Interactions and Use of Volcanic Materials in Pre-Hispanic Cultures of Costa Rica through the Holocene

open access: yesFrontiers in Earth Science, 2018
Critical Zones (CZ) in tropical environments, especially near active volcanoes, are rich in resources such as water, food, and construction materials. In Central America, people have lived near volcanic centers for thousands of years and learned to take ...
Paulo Ruiz   +5 more
doaj   +1 more source

Evaporite karst geohazards in the Delaware Basin, Texas: review of traditional karst studies coupled with geophysical and remote sensing characterization [PDF]

open access: yes, 2017
Evaporite karst throughout the Gypsum Plain of west Texas is complex and extensive, including manifestations ranging from intrastratal brecciation and hypogene caves to epigene features and suffosion caves.
Brown, Wesley A.   +4 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Development of a Wireless Sensor Network for Monitoring an Automated Distributed Water Supply System

open access: yesABUAD Journal of Engineering Research and Development, 2018
[1] Tubaishat, M., & Madria, S. (2003). Sensor networks: an overview. IEEE potentials, vol. 22(2), pp. 20-23. [2] Jiang, P., Xia, H., He, Z., & Wang, Z. (2009). Design of a water environment monitoring system based on wireless sensor networks.
Moses Oluwafemi ONIBONOJE   +2 more
doaj   +1 more source

Environmental Laws in Nigeria and Occurrence of Some Geohazards: A Review [PDF]

open access: yes, 2017
Nigeria as a country is blessed with an abundance of both human and natural resources. Exploitation of natural resources in Nigeria over the years with little or no regard for the environment has increased susceptibility of parts of the country to ...
C. N. Chibo, I. E. Osumgborogwu
core   +3 more sources

The complexities of managing historic buildings with BIM [PDF]

open access: yes, 2020
Purpose The adoption of building information modelling (BIM) in managing built heritage is an exciting prospect, but one that presents complexities additional to those of modern buildings.
Charlton, James   +3 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Electronic Tongue Technology Applied to the Analysis of Grapes and Wines: A Comprehensive Review from Its Origins

open access: yesChemosensors
The electronic tongue (ET) and bioelectronic tongue (bioET) technologies have emerged as innovative and promising tools for the characterization and quality control of complex liquid matrices such as grape musts and wines.
Celia Garcia-Hernandez   +3 more
doaj   +1 more source

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