Results 41 to 50 of about 1,133,444 (262)

Dynamic-Based Limit Analysis for Seismic Assessment of Free-Standing Walls of San Giovanni Church in Castelseprio UNESCO World Heritage Site

Heritage
Free-standing archaeological walls are significantly exposed to horizontal actions (e.g., earthquakes) as they lack connections provided by floors or roofs.
Luca Sbrogiò, Lorenzo Tavano, Ylenia Saretta, Amedeo Caprino, Alejandra Chavarría Arnau, Gian Pietro Brogiolo, Maria Rosa Valluzzi   +6 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Evaluation of the Impact of Courtyard Layout on Wind Effects on Coastal Traditional Settlements

Land
In the context of global climate change, the rising frequency of extreme weather events has increasingly highlighted their impact on human settlements. This study examines the influence of courtyard layout on the wind environment in coastal, traditional ...
Zefa Wang, Tiantian Huang, Yaolong Wang, Shan Dai, Yuee Zeng, Jing Chen, Fengliang Tang   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Development of a smartphone camera-based chemiluminescent lateral flow immunoassay for detecting African swine fever virus antibodies

Frontiers in Microbiology
African swine fever (ASF) is a highly contagious viral disease threatening global swine industries. Rapid and accurate detection of ASF virus (ASFV) antibodies is crucial for disease surveillance and control.
Yaning Sun, Yaning Sun, Suzhen Yang, Yunrui Xing, Lu Fan, Nannan Wang, Qingmei Li, Junqing Guo, Songlin Qiao, Gaiping Zhang, Gaiping Zhang   +10 more
doaj   +1 more source

“It was difficult to offer same day results”: evaluation of community-based point-of-care testing for sexually transmitted infections among youth using the GeneXpert platform in Zimbabwe

BMC Health Services Research, 2022
Background Point-of-care testing for sexually transmitted infections (STIs) may improve diagnosis and treatment of STIs in low- and middle-income counties.
Kevin Martin, Chido Dziva Chikwari, Constance R. S. Mackworth-Young, Mutsawashe Chisenga, Tsitsi Bandason, Ethel Dauya, Ioana D. Olaru, Suzanna C. Francis, Constancia Mavodza, Portia Nzombe, Rangarirayi Nyamwanza, Fadzanai Hove, Maureen Tshuma, Anna Machiha, Katharina Kranzer, Rashida A. Ferrand   +15 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The development and application of an original 3D laser scanning: a precise and nondestructive structural measurements system

Fracture and Structural Integrity, 2020
Recently, a number of non-destructive testings equipment (NDTs) which can partially replace human-conducted onsite inspections has been implemented for detecting modern civil architectural structures.
Kexin Li, Jun Wang, Dawei Qi
doaj   +1 more source

Community engagement on-site rapid test for chlamydia and gonorrhea among men who have sex with men: a pioneering study in Guangzhou, China

BMC Public Health, 2022
Background Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections are prevalent among men who have sex with men (MSM) in China. However, compared to syphilis and HIV, the testing rate for chlamydia and gonorrhea remains low.
Xiao-Xin Lin, Si-Yan Meng, Wu-Jian Ke, Xiao-Hui Zhang, Liu-Yuan Wang, Yu-Ying Liao, Han Liu, Pei-Zhen Zhao, Chun-Mei Liang, Hui-Ru Chen, Hai-Ying Long, Bin Yang, Li-Gang Yang   +12 more
doaj   +1 more source