Results 11 to 20 of about 7,537 (137)

Molecular Screening of Black Flies (Diptera: Simuliidae) for Vector-Borne Zoonotic Pathogens, South Moravia, Czech Republic. [PDF]

open access: yesZoonoses Public Health
ABSTRACT Introduction Black flies (Simuliidae) are globally distributed blood‐feeding arthropods and vectors of viral, bacterial, and parasitic pathogens to many animal species, including humans. We investigated the occurrence of selected vector‐borne pathogens in black flies in South Moravia, Czech Republic, and evaluated their possible role in the ...
Šikutová S   +10 more
europepmc   +2 more sources

Crystal structure of Plasmodium vivax macrophage migration inhibitory factor

open access: yesActa Crystallographica Section F, Volume 82, Issue 6, Page 194-200, June 2026.
The production, crystallization and 1.8 Å resolution crystal structure of macrophage migratory inhibitory factor from P. vivax are reported.Plasmodium vivax is a major cause of malaria globally and has recently been transmitted locally in the USA. P. vivax produces homologs of host proteins, including cytokines such as macrophage migration inhibitory ...
Aryana Nair   +11 more
wiley   +1 more source

Parasite management practices used by owners of Australian Pony Club horses and the factors influencing their decision‐making processes

open access: yesAustralian Veterinary Journal, Volume 104, Issue 5, Page 305-310, May 2026.
There is a lack of information on horse parasite management practices currently used by individual horse owners in Australia. A voluntary, anonymous online survey was developed for and distributed by Pony Club Australia to its members seeking information on horse population; housing; paddock, manure and parasite management; and owner attitudes.
W Nixon, P Buckley, R Butler
wiley   +1 more source

Evolution of Ivermectin Resistance in the Nematode Model Caenorhabditis elegans: Critical Influence of Population Size and Altered Emodepside Efficacy

open access: yesEvolutionary Applications, Volume 19, Issue 4, April 2026.
ABSTRACT The emergence and spread of anthelmintic resistance represent a major challenge for treating parasitic nematodes, threatening mass‐drug administration control programs in humans and zoonotic hosts. Currently, experimental evidence to understand the influence of management (e.g., treatment dose and frequency) and parasite‐associated factors (e ...
Jacqueline Hellinga   +7 more
wiley   +1 more source

Helminths as architects of trained tolerance: implications for human health

open access: yesClinical &Translational Immunology, Volume 15, Issue 3, 2026.
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz   +2 more
wiley   +1 more source

Uncovering the Key Factors Influencing Phytochemical and Phytopharmacological Properties During Medicinal Plant Processing

open access: yeseFood, Volume 7, Issue 1, February 2026.
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley   +1 more source

Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Global efforts to eliminate onchocerciasis are hampered by the lack of a macrofilaricidal drug capable of killing adult parasites. Oxfendazole, a veterinary anthelminthic, exhibits macrofilaricidal activity and holds promise to shorten treatment durations.
Frauke Assmus   +12 more
wiley   +1 more source

Tolerability, Safety, and Pharmacokinetics of Ivermectin After Nasal Application in Healthy Adult Subjects

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Nasal epithelium is the site of infection for SARS‐CoV2 viruses, with interactions of the viral spike protein with the ACE2 receptor of the host cell. Molecular docking studies have shown that ivermectin shields the spike protein and thereby prevents binding to ACE2.
Stefan Wissel   +5 more
wiley   +1 more source

Intestinal Parasites of Zoonotic Significance in Human and Domestic Animals in a Rural Setting in Nepal

open access: yesVeterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Intestinal parasites are shared among humans and domestic animals. Rural setting is critical to enhance parasite zoonosis in Nepal. ABSTRACT Intestinal parasitic (IP) species with zoonotic significance are major public health issues, mostly prevalent in developing countries, leading to high morbidity and mortality. The present study aimed to assess the
Prince Rai, Tirth Raj Ghimire
wiley   +1 more source

Comparative Analysis of Gut Microbiomes in Parasitic Roundworms Reveals Phylogeny‐Associated Community Structure and Functional Adaptation

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Roundworm nematodes are globally distributed zoonotic parasites that inhabit the intestinal tract of various mammals. Although these parasites reside in the host’s guts, their own intestinal ecosystems remain poorly understood. Recent evidence suggests that helminths may harbor distinct gut microbiomes that contribute to their physiology and host ...
Xinyi Fan   +9 more
wiley   +1 more source

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