Results 111 to 120 of about 845,274 (281)

Oncogenic Potential of Replication Factor C Subunit 4: Correlations with Tumor Progression and Assessment of Potential Inhibitors

Pharmaceuticals
Replication Factor C Subunit 4 (RFC4), an oncogene implicated in many human cancers, has yet to be extensively studied in many cancer types to determine its expression patterns and tumor tissue function.
Muhammad Alaa Eldeen, Farag Mamdouh, Waleed K. Abdulsahib, Refaat A. Eid, Ahmad A. Alhanshani, Ayed A. Shati, Youssef A. Alqahtani, Mohammed A. Alshehri, Mohamed Samir A. Zaki, Mohamed A. Soltan, Ahmed E. Noreldin   +10 more
doaj   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

C-myc oncogene product P62c-myc in ovarian mucinous neoplasms: immunohistochemical study correlated with malignancy. [PDF]

, 1989
S V Polacarz, N A Hey, Terence Stephenson, Annette Hill   +3 more
openalex   +1 more source

Data from Array-Based Comparative Genomic Hybridization Analysis Identified Cyclin D1 as a Target Oncogene at 11q13.3 in Nasopharyngeal Carcinoma

, 2023
Angela Bik‐Yu Hui, Yvonne Yan‐Yan Or, Hirokuni Takano, Raymond King‐Yin Tsang, Ka‐Fai To, Xin-Yuen Guan, Jonathan S. T. Sham, Katherine Wing-Ki Hung, Cleo Nga-Yee Lam, C. Andrew van Hasselt, Wen-Lin Kuo, Joe W. Gray, Dolly P. Huang, Kwok Wai Lo   +13 more
openalex   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

p53 oncogene mutations in head and neck cancer based on the weighted Euclidean distance [PDF]

, 2012
Juanjuan Kong, Ping Zhu
openalex   +1 more source

Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells. [PDF]

, 2012
MicroRNAs are often associated with the pathogenesis of many cancers, including head and neck squamous cell carcinoma (HNSCC). In particular, microRNA-21 (miR-21) appears to have a critical role in tumor cell survival, chemoresistance and HNSCC ...
Bourguignon, LYW, Earle, C, Krueger, K, Spevak, CC, Wong, G   +4 more
core  

The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma

, 2016
The REL gene, encoding the NF-κB subunit c-Rel, is frequently amplified in B-cell lymphoma and functions as a tumour-promoting transcription factor. Here we report the surprising result that c-rel–/– mice display significantly earlier lymphomagenesis in ...
Bacon, C.M., Butterworth, J.A., Campbell, K.J., Cockell, S.J., Gewurz, B.E., Hunter, J.E., Perkins, N.D., Sellier, H., Thomas, H.D., Zhao, B.   +9 more
core   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Protein tyrosine kinase 6 (PTK6; BRK); epidermal growth factor receptor (EGFR; ERBB1; HER1); v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (ERBB2; HER2; Neu) [PDF]

, 2008

openalex   +1 more source