Results 211 to 220 of about 617,669 (345)
RFLP for TaqI of the human thyroid papillary carcinoma (PTC) oncogene [PDF]
, 1988 Paolo Radice +8 more
openalex +1 more source
Advanced Science, EarlyView.To solve the challenge of PROTACs in clinical potential due to poor water solubility and membrane permeability, a nanodelivery system based on lipid nanodisks loaded with MZ1 prodrug (LND‐MZ1) to remodel the physicochemical and pharmacokinetic properties of PROTAC MZ1 is elaborately proposed.
Meichen Pan +6 more
wiley +1 more source
Retraction Note: β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma. [PDF]
OncogeneLu Y +9 more
europepmc +1 more source
Structure and expression of the oncogene c-myc in fresh tumor material from patients with hematopoietic malignancies. [PDF]
, 1984 Paul G. Rothberg +4 more
openalex +1 more source
Advanced Science, EarlyView.During the progression of CRC, MDM2, as an E3 ubiquitin ligase, promotes the degradation of the LLGL2 protein. Reduced expression of the LLGL2 protein leads to the loss of support for the CNOT1 protein, decreasing the degradation of THBS3 mRNA. The increased THBS3 further activates the PI3K‐Akt pathway, promoting the proliferation and metastasis of CRC.
Jiayan Huang +8 more
wiley +1 more source
Serum screening for oncogene proteins in workers exposed to PCBs. [PDF]
, 1988 Paul W. Brandt‐Rauf, Henry Niman
openalex +1 more source
Advanced Science, EarlyView.Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao +13 more
wiley +1 more source
Effective IHH gene knockout by CRISPR/Cas9 system in chicken DF-1 cells. [PDF]
Poult SciJin S +8 more
europepmc +1 more source
Replication of proto-oncogenes early during the S phase in mammalian cell lines
, 1987 Mohammed A. Iqbal +3 more
openalex +1 more source