Results 301 to 310 of about 250,918 (350)

Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy

Cancer Communications, EarlyView.
Abstract Background Pancreatic cancer's aberrant lipid metabolism fuels cell growth, invasion, and metastasis, yet its impact on immune surveillance and immunotherapy is unclear. This study investigated how sterol regulatory element‐binding transcription factor 1 (SREBP1)‐driven lipid metabolism affects the tumor microenvironment (TME) in pancreatic ...
Mengyi Lao, Xiaozhen Zhang, Zejun Li, Kang Sun, Hanshen Yang, Sicheng Wang, Lihong He, Yan Chen, Hanjia Zhang, Jiatao Shi, Daqian Xu, Tingbo Liang, Xueli Bai   +12 more
wiley   +1 more source

Super-enhancers in tumors: unraveling recent advances in their role in Oncogenesis and the emergence of targeted therapies. [PDF]

J Transl Med
Ji Y, Li B, Lin R, Yuan J, Han Y, Du Y, Zhao Y.   +6 more
europepmc   +1 more source

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

Chemistry &Biodiversity, Accepted Article.
Objective: Cancer remains a global health challenge, necessitating new therapeutic options. Phytochemicals, with diverse chemical structures and biological activities, show promise as anticancer agents. This review explores key phytochemicals, their mechanisms, and their potential integration into cancer therapy.
Alaa A. A. Aljabali, Mohammad A. Obeid, Rasha M. Bashatwah, Esam Qnais, Omar Gammoh, Abdelrahim Alqudah, Vijay Mishra, Yachana Mishra, Mohammad Ahmed Khan, Suhel Parvez, Mohamed El-Tanani, Taher Hatahet   +11 more
wiley   +1 more source

Unveiling the mysteries of extrachromosomal circular DNA: from generation to clinical relevance in human cancers and health. [PDF]

Mol Cancer
Wang Z, Yu J, Zhu W, Hong X, Xu Z, Mao S, Huang L, Han P, He C, Song C, Xiang X.   +10 more
europepmc   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma

Cancer Communications, EarlyView.
Katia Mariniello, James F. H. Pittaway, Barbara Altieri, Kleiton Silva Borges, Irene Hadjidemetriou, Claudio Ribeiro, Gerard Ruiz‐Babot, David S. Tourigny, Jiang A. Lim, Julie Foster, Julie Cleaver, Jane Sosabowski, Nafis Rahman, Milena Doroszko, Constanze Hantel, Sandra Sigala, Andrea Abate, Mariangela Tamburello, Katja Kiseljak‐Vassiliades, Margaret Wierman, Charlotte Hall, Laila Parvanta, Tarek E. Abdel‐Aziz, Teng‐Teng Chung, Aimee Di Marco, Fausto Palazzo, Celso E. Gomez‐Sanchez, David R. Taylor, Oliver Rayner, Cristina L. Ronchi, Carles Gaston‐Massuet, Silviu Sbiera, William M. Drake, Emanuel Rognoni, Matthias Kroiss, David T. Breault, Martin Fassnacht, Leonardo Guasti   +37 more
wiley   +1 more source

Rotenoids from the Roots of Vicia faba L. (Fabaceae): Structural Characterization, Cytotoxic Effects, and Molecular Docking

Chemistry &Biodiversity, EarlyView.
ABSTRACT The chemical study of the ethanolic extract from the roots of Vicia faba led to the isolation of two isoflavonoids, alfalone and 8‐O‐methylretusine, as well as a mixture of rotenoids, including clitoriacetal and clitoriacetal B, the latter of which is reported for the first time.
Victor Menezes Sipoloni, João Victor Silva‐Silva, Elthon G. Ferreira, Eric Yoshitaka Lee, João Marcos Batista Junior, Miriam Uemi, Lívia Soman de Medeiros, Paula C. Jimenez, Thiago A. M. Veiga   +8 more
wiley   +1 more source

Factores de riesgo de cáncer bucal

Revista Cubana de Estomatología
Pedro Antonio Miguel Cruz, Aluett Niño Peña, Kelia Batista Marrero, Pedro Enrique Miguel-Soca   +3 more
doaj  

Author Correction: Neutrophil extracellular traps promote metastasis in gastric cancer patients with postoperative abdominal infectious complications. [PDF]

Nat Commun
Xia X, Zhang Z, Zhu C, Ni B, Wang S, Yang S, Yu F, Zhao E, Li Q, Zhao G.   +9 more
europepmc   +1 more source