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40 years of LEUKEMIA. [PDF]

open access: yesLeukemia
Hochhaus A, Gale RP.
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Oncogenes

The Journal of Pathology, 1984
A barrage of information is now emerging about one of the thorniest and most significant problems in biology: the nature of the genetic events that trigger neoplasia. While the notion that cancer reflects somatic mutations is several decades old, only in the last few years could the relevant 'oncogenes' be identified and put to molecular dissection ...
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Oncogenes and proto-oncogenes

Journal of Cellular Physiology, 1983
The discovery that normal cells contain proto-oncogenes--genes that are analogous to known viral oncogenes--may provide a shortcut not only to understanding some of the pathophysiologic mechanisms that must be involved in carcinogenesis but also to dissecting the processes of normal cell growth and of the evolutionarily developed controls on such ...
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