Results 141 to 150 of about 80,296 (266)

Stat proteins and oncogenesis [PDF]

Journal of Clinical Investigation, 2002
openaire   +2 more sources

Novel and emerging skin carcinomas and adnexal tumours

Histopathology, EarlyView.
The present review aims to provide an overview of the main emerging skin epithelial tumours, with particular emphasis on salivary gland analogue sweat gland tumours and poorly differentiated carcinomas. Epidermal and adnexal tumours of the skin constitute a complex and heterogeneous group of neoplasms, with distinct morphology and behaviour.
Thibault Kervarrec, Maxime Battistella, Nicolas Macagno   +2 more
wiley   +1 more source

Dynamic DNA methylation changes during colorectal oncogenesis with insights from adenoma stages. [PDF]

Sci Rep
Overs A, Molimard C, Durand J, Bibeau F, Arnould L, Monnien F, Clavier C, Borg C, Guittaut M, Feugeas JP, Hervouet E, Peixoto P, Selmani Z.   +12 more
europepmc   +1 more source

HMGA2 is a highly sensitive marker for DICER1‐related tumours

Histopathology, EarlyView.
Aims DICER1 is a microRNA biogenesis enzyme that, when mutated, results in a rewiring of the transcriptome. Germline pathogenic variants (PVs) in DICER1 result in DICER1‐related tumour predisposition (DRTP) characterized by 30 or more different, generally rare, paediatric or adolescent‐onset tumours.
Paul S. Thorner, Anne‐Laure Chong, Naciba Benlimane, Lili Fu, Marc R. Fabian, William D. Foulkes   +5 more
wiley   +1 more source

Alternatively activated macrophages cause DNA damage through an arginase 1-mediated bystander effect and promote epithelial cell transformation. [PDF]

Oncogenesis
Undi RB, Sutton MM, Becker E, Gordon M, Vesely SK, Ricketts S, Velayutham R, Tierney WM, Houchen CW, Ali N, Huycke MM.   +10 more
europepmc   +1 more source

Cutaneous Leiomyosarcoma of the Skin: An Updated Review of Epidemiology, Pathogenesis, and Management

International Journal of Dermatology, EarlyView.
This review provides an update on the epidemiology, pathogenesis, and clinical/histologic features of cutaneous leiomyosarcoma. Prognostic factors (e.g., depth of tumor involvement, grade, etc.) that can facilitate risk stratification are also discussed, as are treatment approaches for this rare malignancy.
Tejas P. Joshi, Natalie Garcia, Malak Husseinali, Nabeeha Engineer, Ikue Shimizu   +4 more
wiley   +1 more source

The Emerging Role of UCHL1 in Neurological and Musculoskeletal Diseases

Immunology &Cell Biology, EarlyView.
UCHL1‐associated pathology. The pathological role of UCHL1 in multisystem diseases, including cancer, neurological, musculoskeletal and cardiovascular disorders. ABSTRACT Ubiquitin C‐terminal hydrolase L1 (UCHL1) is a highly conserved deubiquitinating enzyme that has transitioned from being viewed as a “brain‐specific” protein to a global regulator of ...
Ru Feng, Xiu Zhong, Jianjun Li, Adrian A. Achuthan   +3 more
wiley   +1 more source

Special Issue "New Insights into the Effects of Microbiome-Derived Metabolites on Health and Disease". [PDF]

Int J Mol Sci
Jaworska K.
europepmc   +1 more source

Oral and Pancreatobiliary Microbiota in Cancer: A Systematic Review of Compositional Alterations and Their Clinical Implications

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Associations between microbial dysbiosis and malignancies of the pancreatobiliary system have been described in recent studies. As a result of the limited number of studies that have been done specifically on the malignancies of the biliary tract, information regarding oral, biliary and tumour‐related microbial alterations was ...
Esperouz Fariba, Villani Rosanna, Ciavarella Domenico, Serviddio Gaetano, Lorusso Mauro, Lo Russo Lucio   +5 more
wiley   +1 more source

Editorial: Oncogenic RAS-Dependent Reprogramming of Cellular Plasticity

Frontiers in Oncology, 2020
Georgia Konstantinidou, Alessandro Rimessi   +1 more
doaj   +1 more source