Results 251 to 260 of about 137,458 (285)
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2014
Human papillomaviruses (HPVs) are epitheliotropic viruses which cause a variety of lesions at cutaneous and mucosal sites. Lesions range from the benign wart to dysplasia and neoplasia. Importantly, HPV has been shown to be etiological in several malignancies including cervical cancer, other anogenital cancers, oropharyngeal cancers, and cutaneous ...
Hung Q, Doan +2 more
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Human papillomaviruses (HPVs) are epitheliotropic viruses which cause a variety of lesions at cutaneous and mucosal sites. Lesions range from the benign wart to dysplasia and neoplasia. Importantly, HPV has been shown to be etiological in several malignancies including cervical cancer, other anogenital cancers, oropharyngeal cancers, and cutaneous ...
Hung Q, Doan +2 more
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Neurocysticercosis and Oncogenesis
Archives of Medical Research, 2000Recent studies suggest that neurocysticercosis may be a risk factor for human cancer. Pathogenetic mechanisms explaining possible oncogenic effects of cysticerci include the following: (a) parasite-induced modulation of the host immune response that may be associated with loss of regulatory mechanisms implicated in the immunological surveillance ...
O H, Del Brutto +3 more
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The American Journal of Medicine, 1987
For more than a century, medical investigators have sought to incriminate microorganisms in the cause of cancer. The first scientific evidence of such a relationship came in 1911, with the first successful induction of a tumor using a cell-free extract.
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For more than a century, medical investigators have sought to incriminate microorganisms in the cause of cancer. The first scientific evidence of such a relationship came in 1911, with the first successful induction of a tumor using a cell-free extract.
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Human Papillomavirus Oncogenesis
Clinics in Laboratory Medicine, 2000HPVs have evolved to accomplish the task of controlling host cell proliferation and differentiation to the end of producing more infectious virions. Coincident with the viral life cycle, however, is the risk that the viral genome will be disrupted and its DNA integrated into the host cell chromosomes.
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Phylogenesis — Ontogenesis — Oncogenesis
Medical Hypotheses, 1989Ontogenesis might be considered as the development of phylogenetically consequent genic systems that mainly imply: homoeotic genes and ras protooncogene in segmentation; ras and myc protooncogenes in gastrulation; ras, myc and other nuclear protooncogenes in organogenesis; ras myc, other nuclear and cytomembrane protooncogenes in growth-differentiation.
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2015
This paper reviews current theories on the etiology of acquired immunodeficiency syndrome (AIDS) recent advances in the mechanisms of oncogenesis and the relationship of immunodeficiency to the development of cancer. It then attempts to synthesize these concepts into a hypothesis to explain the AIDS-cancer connection.
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This paper reviews current theories on the etiology of acquired immunodeficiency syndrome (AIDS) recent advances in the mechanisms of oncogenesis and the relationship of immunodeficiency to the development of cancer. It then attempts to synthesize these concepts into a hypothesis to explain the AIDS-cancer connection.
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Evolutionary maintenance of oncogenesis
Journal of Cancer Research and Clinical Oncology, 2008Transformation of normal cells into cells with malignant phenotypes is often the result of loss of tumor suppressor gene (TSG) function after exposure to a carcinogen.We propose that TSGs susceptible to mutation and consequent loss of function are evolutionarily preserved in normal cell genomes so that the cells survive mutation-inducing insults and ...
Steven M, Sorscher +2 more
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Molecular Mechanisms of Oncogenesis
1990Cellular oncogenes (c-oncs) have been highly conserved throughout evolution and subserve important roles in growth and development. Both in development and the neoplastic state, c-oncs appear to collaborate rather than function independently. Cellular oncogenes are activated in the neoplastic process by four (nonviral) mechanisms; (a) chromosomal ...
T A, Seemayer, W K, Cavenee
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Journal of the National Medical Association, 1980
Two patients who were treated with therapeutic doses of ionizing radiation for primary carcinoma of the thyroid and cervix developed a second malignancy in the organs included in the field of radiation 10 and 14 years later, respectively. These two patients, whose second malignancies meet all of the criteria to be classified as radiation induced cancer,
P P, Kumar, J R, Newland
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Two patients who were treated with therapeutic doses of ionizing radiation for primary carcinoma of the thyroid and cervix developed a second malignancy in the organs included in the field of radiation 10 and 14 years later, respectively. These two patients, whose second malignancies meet all of the criteria to be classified as radiation induced cancer,
P P, Kumar, J R, Newland
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Bulletin du cancer, 2010
Recent progress in the field of molecular biology has allowed us to identify at least two different molecular mechanisms implicated in colorectal carcinogenesis (CRC): chromosomal instability (CIN) and genetic instability. Even though the two molecular mechanisms differ, their signalling pathways, implicated in malignant transformation of colonic ...
P, Laurent-Puig, J, Agostini, K, Maley
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Recent progress in the field of molecular biology has allowed us to identify at least two different molecular mechanisms implicated in colorectal carcinogenesis (CRC): chromosomal instability (CIN) and genetic instability. Even though the two molecular mechanisms differ, their signalling pathways, implicated in malignant transformation of colonic ...
P, Laurent-Puig, J, Agostini, K, Maley
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