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Human Papillomavirus Oncogenesis
Clinics in Laboratory Medicine, 2000HPVs have evolved to accomplish the task of controlling host cell proliferation and differentiation to the end of producing more infectious virions. Coincident with the viral life cycle, however, is the risk that the viral genome will be disrupted and its DNA integrated into the host cell chromosomes.
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Papillomaviruses and human oncogenesis
Current Biology, 1992During the past year, significant advances have been made in understanding the functions of the oncoproteins, E6 and E7, of human papillomaviruses that are associated with malignant genital tumors. In addition, important new information is now available on the responses of both the keratinocyte and of the individual following papillomavirus infection.
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Molecular themes in oncogenesis
Cell, 1991At present ,lesions in the proto-oncogenes and tumor suppressor genes seem almost equally prevalent among human cancers ,although the number of tumor suppressor genes afflicted in any given tumor may be greater ,and examples exist in wich only one (or even no) genetic lesion has been detected .It seems likely ,however thatmost malignancies arise from ...
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HOCl and the control of oncogenesis
Journal of Inorganic Biochemistry, 2018Sustained generation of extracellular superoxide anions by membrane-associated NADPH oxidase-1 is a hallmark of malignant transformation. The resulting H2O2 drives the proliferation of malignant cells and is converted to HOCl by a Dual oxidase-related peroxidase domain that acts analogously to myeloperoxidase.
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Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1993
T, Motokura, A, Arnold
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T, Motokura, A, Arnold
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Stochastic theory of oncogenesis.
Anticancer research, 1990It is generally agreed that most malignancies, particularly those that arise "spontaneously", are caused by randomly occurring mutations at specific sites of the genome. Hence oncogenesis of these spontaneous tumors can be described by stochastic mathematical models. In this paper we offer a mathematical approach to oncogenesis.
Boxma, O.J. +3 more
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Colorectal Cancer: From Risk Factors to Oncogenesis
Medicina (Lithuania), 2023Camelia Diaconu +2 more
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Recent Insight about HE4 Role in Ovarian Cancer Oncogenesis
International Journal of Molecular Sciences, 2023Emanuela Anastasi +2 more
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