Results 211 to 220 of about 80,296 (266)
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Neurocysticercosis and Oncogenesis
Archives of Medical Research, 2000Recent studies suggest that neurocysticercosis may be a risk factor for human cancer. Pathogenetic mechanisms explaining possible oncogenic effects of cysticerci include the following: (a) parasite-induced modulation of the host immune response that may be associated with loss of regulatory mechanisms implicated in the immunological surveillance ...
O H, Del Brutto +3 more
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The American Journal of Medicine, 1987
For more than a century, medical investigators have sought to incriminate microorganisms in the cause of cancer. The first scientific evidence of such a relationship came in 1911, with the first successful induction of a tumor using a cell-free extract.
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For more than a century, medical investigators have sought to incriminate microorganisms in the cause of cancer. The first scientific evidence of such a relationship came in 1911, with the first successful induction of a tumor using a cell-free extract.
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2014
Human papillomaviruses (HPVs) are epitheliotropic viruses which cause a variety of lesions at cutaneous and mucosal sites. Lesions range from the benign wart to dysplasia and neoplasia. Importantly, HPV has been shown to be etiological in several malignancies including cervical cancer, other anogenital cancers, oropharyngeal cancers, and cutaneous ...
Hung Q, Doan +2 more
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Human papillomaviruses (HPVs) are epitheliotropic viruses which cause a variety of lesions at cutaneous and mucosal sites. Lesions range from the benign wart to dysplasia and neoplasia. Importantly, HPV has been shown to be etiological in several malignancies including cervical cancer, other anogenital cancers, oropharyngeal cancers, and cutaneous ...
Hung Q, Doan +2 more
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Transgenic Mice and Oncogenesis
Annual Review of Immunology, 1988The creation of transgenic mice carrying specific cancer-promoting genes has opened an exciting new era in oncology. The biological effects of an individual oncogene on diverse cell types can now be assessed directly within the living animal. While transgenic animals bear the introduced oncogene in every tissue, expression of that gene may either be ...
S, Cory, J M, Adams
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Oncogenesis in cholangiocarcinoma
Cholangiocarcinoma (CCA), a highly heterogeneous malignancy of the biliary tract, has emerged as a global health concern due to its rising incidence and poor prognosis. Its pathogenesis is shaped by complex interactions between environmental, infectious, and genetic factors, leading to dysregulation of key cellular pathways and molecular alterations ...Rares Ilie, Orzan, Andrada, Seicean
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Retinoblastoma: A Model of Oncogenesis
Ophthalmology, 1984Early events in oncogenesis can be understood in retinoblastoma (RB) because of several unusual clinical features: intraocular location of the tumor results in early diagnosis and frequent cure by surgery; survivors demonstrate a dominantly transmitted hereditary predisposition to RB; heritable and nonheritable subgroups can usually be distinguished ...
B L, Gallie, R A, Phillips
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Oncogenesis by phase separation
Nature Reviews Genetics, 2021A new study by Ahn et al. shows that chimeric proteins containing intrinsically disordered regions mediate oncogenesis by inducing liquid–liquid phase separation and thereby affecting chromatin conformation and transcription.
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Molecular Mechanisms of Oncogenesis
1990Cellular oncogenes (c-oncs) have been highly conserved throughout evolution and subserve important roles in growth and development. Both in development and the neoplastic state, c-oncs appear to collaborate rather than function independently. Cellular oncogenes are activated in the neoplastic process by four (nonviral) mechanisms; (a) chromosomal ...
T A, Seemayer, W K, Cavenee
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