Results 91 to 100 of about 1,580,994 (358)

Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology.

Journal of Clinical Oncology, 2018
Purpose To provide guidance regarding the practical assessment and management of vulnerabilities in older patients undergoing chemotherapy. Methods An Expert Panel was convened to develop clinical practice guideline recommendations based on a systematic ...
S. Mohile, W. Dale, M. Somerfield, M. Schonberg, C. Boyd, P. Burhenn, B. Canin, H. Cohen, H. Holmes, J. Hopkins, M. Janelsins, A. Khorana, H. Klepin, S. Lichtman, K. Mustian, W. Tew, A. Hurria   +16 more
semanticscholar   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Interleukin-6 as a Predictive Marker for Lymph Node and Distant Metastasis in Colorectal Cancer: A Retrospective Cohort Study

Cancer Management and Research
Jianjun Xiao, Muyou Tian, Guoyu Chen, Huifen Li Department of Medical Oncology, Zhongshan City People’s Hospital, Zhongshan, Guangdong, People’s Republic of ChinaCorrespondence: Huifen Li, Department of Medical Oncology, Zhongshan City People’s Hospital,
Xiao J, Tian M, Chen G, Li H
doaj  

The effect of vascular endothelial growth factor-1 expression on survival of advanced colorectal cancer patients

Libyan Journal of Medicine, 2017
Colorectal cancer is third leading cause of cancer mortality. About 60% of patients had already developed metastasis at the time of diagnosis. Vascular endothelial growth factor (VEGF) is crucial for the development of neovascularization and hence ...
Riyad Bendardaf, Ahmed El-Serafi, Kari Syrjänen, Yrjö Collan, Seppo Pyrhönen   +4 more
doaj   +1 more source

Defining the biological basis of radiomic phenotypes in lung cancer

eLife, 2017
Medical imaging can visualize characteristics of human cancer noninvasively. Radiomics is an emerging field that translates these medical images into quantitative data to enable phenotypic profiling of tumors.
Patrick Grossmann, Olya Stringfield, Nehme El-Hachem, Marilyn M Bui, Emmanuel Rios Velazquez, Chintan Parmar, Ralph TH Leijenaar, Benjamin Haibe-Kains, Philippe Lambin, Robert J Gillies, Hugo JWL Aerts   +10 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Expression of Concern: Case report: A rare case of tumor-to-tumor metastasis: metastatic lobular breast carcinoma to clear cell renal cell carcinoma

Pathology and Oncology Research, 2023
Pathology & Oncology Research Editorial Office
doaj   +1 more source

Oncological treatment and outcome of colorectal cancer in Greenland

International Journal of Circumpolar Health, 2018
Oncological treatment of colorectal cancer (CRC) has been available in Greenland since 2004. Treatment is provided by Queen Ingrid´s Hospital (QIH), under supervision from the Department of Oncology, Rigshospitalet, Denmark.
Marie Odgaard, Nicolai Lohse, Alice Juhl Petersen, Lene Bæksgaard   +3 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Humanized mouse models for immuno-oncology research

Nature Reviews Clinical Oncology, 2023
Jane Chuprin, Hannah Buettner, Mina O Seedhom, D. Greiner, J. Keck, F. Ishikawa, L. Shultz, M. Brehm   +7 more
semanticscholar   +1 more source