Author Correction: Combination of PARP and KRAS<sup>G12D</sup> inhibitors enhances therapeutic efficacy by exploiting vulnerabilities in PDAC. [PDF]
Xu X +9 more
europepmc +1 more source
Two-and-a-half-year clinical experience with the world\u27s first magnetic resonance image guided radiation therapy system [PDF]
Acharya, Sahaja +23 more
core +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Hydrogel spacer distribution within the perirectal space in patients undergoing radiotherapy for prostate cancer: Impact of spacer symmetry on rectal dose reduction and the clinical consequences of hydrogel infiltration into the rectal wall [PDF]
Bosch, Walter +4 more
core +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Correction: Evaluating the role of consolidative chest radiotherapy after chemo‑immunotherapy in extensive‑stage small cell lung cancer: a retrospective study. [PDF]
Vazquez-Urrutia JR +5 more
europepmc +1 more source
The Oncology Care Model: Oncology\u27s First Foray Away From Volume and Toward Value-Based Care. [PDF]
Csik, Valerie P. +3 more
core +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Digital health technology in oncology: results from a survey by the ESMO Young Oncologists Committee and medical student alumni. [PDF]
Mandó P +25 more
europepmc +1 more source

