Results 121 to 130 of about 165,320 (303)

Feasibility of capturing radiation oncology quality metrics in a large integrated oncology practice.

, 2017
83 Background: Metrics to assess quality are important to improve processes of care. While such capture and reporting are common in medical oncology practices, it is less common with radiation oncology.
Jeff Bernard, Lalan S. Wilfong, Jeffrey Limmer, John Russell Hoverman, Ajay Dubey, Bret Heintz, Kyle Antes, Stacy Hartman, Bernard Taylor, Brennan Scott Cheek   +9 more
core   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Cancer Survivorship in 10 Asia Pacific Countries: What can we learn from a study of 1873 cancer survivors and 1501 oncology practitioners?

, 2018
Background: Gaining an understanding of perspectives of patients and oncology practitioners can inform the design of interventions and service planning in the Asia-Pacific region. This study aimed to examine the supportive care needs of cancer survivors;
Yates, Patsy, Molasiotis, Alex, Chan, Raymond   +2 more
core  

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source

Creating a radiation oncology oriented safety culture within a large oncology practice: Lessons learned.

, 2017
85 Background: Texas Oncology (TXO) is a dedicated oncology practice consisting of more than 400 physicians and 57 radiation oncologists at 52 sites of service.
Jeff Bernard, Lalan S. Wilfong, Jeffrey Limmer, John Russell Hoverman, Ajay Dubey, Bret Heintz, Kyle Antes, Stacy Hartman, Bernard Taylor, Brennan Scott Cheek   +9 more
core   +1 more source

Matrix Stiffness Induces Endothelial Network Senescence

Advanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song, Alexandra N. Rindone, Ya Guan, Connor D. Amelung, Prarthana Sanjay Daswani, Jennifer H. Elisseeff, Sharon Gerecht   +6 more
wiley   +1 more source

Real world outcomes of a virtual ocular oncology service in Scotland. [PDF]

Eye (Lond), 2023
Younus O, Gillam M, Cauchi P, Chadha V, Connolly J.   +4 more
europepmc   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

Ocular oncology service during the COVID-19 outbreak: uveal melanoma characteristics presenting in 2019 compared to 2020. [PDF]

Ir J Med Sci, 2023
Mc Glacken-Byrne A, Murtagh P, O'Neill V, Horgan N.   +3 more
europepmc   +1 more source

Contemporary Regional Disparities in Robotic‐Assisted Rectal Resection in Japan: A Nationwide Population‐Based Study Using the National Database Open Data

Annals of Gastroenterological Surgery, EarlyView.
Robotic‐assisted rectal resection in Japan increased markedly after national insurance reimbursement in 2018, with a concurrent decline in open surgery. Using NDB Open Data, we found substantial inter‐prefectural heterogeneity in surgical volume and robotic utilization that persisted after age and sex standardization (SCR). Urban–rural differences were
Ryo Ohta, Takeshi Yamada, Key Uehara, Hiromichi Sonoda, Akihisa Matsuda, Seiichi Shinji, Yasuyuki Yokoyama, Goro Takahashi, Nobuhiko Taniai, Hiroshi Yoshida   +9 more
wiley   +1 more source