Results 101 to 110 of about 165,320 (303)

Coexpression of p-IGF-1R and MMP-7 Modulates Panitumumab and Cetuximab Efficacy in RAS Wild-Type Metastatic Colorectal Cancer Patients

Neoplasia: An International Journal for Oncology Research, 2018
INTRODUCTION: The coexpression of pIGF-1R and MMP-7 (double-positive phenotype, DP) correlates with poor overall survival (OS) in KRAS wild-type (WT) (exon 2) metastatic colorectal cancer (mCRC) patients treated with irinotecan-cetuximab in second/third ...
Vicente Alonso, Pilar Escudero, Carlos Fernández-Martos, Antonia Salud, Miguel Méndez, Javier Gallego, Jose-R. Rodriguez, Marta Martín-Richard, Julen Fernández-Plana, Hermini Manzano, José-Carlos Méndez, Monserrat Zanui, Esther Falcó, Mireia Gil-Raga, Federico Rojo, Miriam Cuatrecasas, Jaime Feliu, Xabier García-Albéniz, Joan Maurel   +18 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Impact of a dedicated inpatient radiation oncology consult service on goal-concordant care

Purpose: Radiation therapy has an increasing role in the management of metastatic cancers. Integrating radiation with surgical and systemic approaches is complex, and inappropriate management can lead to prolonged hospitalizations inconsistent with ...
Yerramilli, Divya, Freret, Morgan E., Cahlon, Oren, Brennan, Victoria S., Tsai, C. Jillian, Powell, Simon N., Xu, Amy J., Yang, Jonathan T., Boe, Lillian A., McBride, Sean, Iyengar, Puneeth, Gomez, Daniel R.   +11 more
core   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Development and Implementation of Cardio-oncology Services at the National Center for Cancer Care and Research and Heart Hospital: The Qatar Experience

Heart Views
Background: cardiovascular disease and cancer are two leading causes of mortality worldwide. Advances in cancer therapy have improved survival but increased the risk of treatment-related cardiotoxicity.
Asma Mohammad Younus AlBulushi, Kalpana Singh, Salma Suliman Ibnouf, Jassim Zaheen Shah, Rasha Kaddoura, Salha Bujassoum Al Bader, Wafer Amen Dabdoob, Wafaa Naeem Shehada, Eyad Mohammad Tubishat, Nima Ahmad Ali   +9 more
doaj   +1 more source

A service evaluation: EllenorLions Hospices Children and Young Peoples Service: Executive Summary [PDF]

, 2011
Between January and June 2011, the EllenorLions Hospices commissioned a team from Canterbury Christ Church University to independently review the Children and Young Peoples Service to evaluate the integrated service model which delivers both palliative ...
Teasdale, D., Ruston, A., Summers, K.
core  

3D‐Nanoprinted Fluidically Steerable Soft Robotic Microcatheters

Advanced Robotics Research, EarlyView.
This work introduces a ∼3‐French (1 mm‐in‐diameter) soft robotic microcatheter fabricated by means of two‐photon direct laser writing. The 3D‐printed microcatheter enables remote, on‐demand steering via microfluidic actuation for guidewire‐free navigation of vascular networks as well as microcatheter‐mediated delivery of fluidic payloads to target ...
Bailey M. Felix, Molly Carton, Olivia M. Young, Noah Barnes, Jordi T. Andreou, Sarah McHugh, Jack E. McCann, Claudia Davis, Victoria Reddig‐Leiman, Afsah Kamran, Dheeraj Gandhi, Miroslaw Janowski, Jeremy D. Brown, Mark Fuge, Axel Krieger, Clifford R. Weiss, Christopher R. Bailey, Ryan D. Sochol   +17 more
wiley   +1 more source

Cardio-Oncologic Knowledge of Nurses in the Oncology Service: A Multi-Center Survey in China. [PDF]

J Multidiscip Healthc, 2023
Zhang C, Yang Z, Du R, Feng Y, Zhang X, Zhang J.   +5 more
europepmc   +1 more source

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang, Ning Lu, Zhuo Yan, Luyi Ye, Luyao Bai, Shanshan Yuan, Yuting Zhu, Yiru Xiong, Yongheng Bai, Yaping Chen, Junjie Deng   +10 more
wiley   +1 more source

The state of cardio-oncology in Oman: awareness, practices, and training needs among healthcare providers: a survey-based study

Cardio-Oncology
Background Cardio-oncology has emerged as a multidisciplinary subspecialty to address the growing burden of cancer therapy–related cardiovascular toxicity and its impact on morbidity and mortality.
Ahmed Basuoni, Bushra Salman, Khalid Al-Baimani, Suhaila Al Farsi, Waleed Dawelbeit, Mohamed Barakat Al Riyami, Marwa Ahmed Makhlouf, Issa Al Qarshoubi, Adil Barakat Al Riyami, Mohamed Najeeb Al Rawahi   +9 more
doaj   +1 more source