Results 1 to 10 of about 45,847 (254)

Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study [PDF]

BMC Veterinary Research, 2017
Nausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to determine the efficacy of three classes of antiemetic drugs in a novel low dose cisplatin model of nausea and vomiting and measure change
A Freeman, A Tidholm, AM Holmes, B Otto, C Pirri, C Rojas, CC Horn, CC Horn, CJ Henry, DB Smith, DB Zamble, DG Warr, F Roila, F Roila, FD Tattersall, GJ Sanger, GJ Sanger, GR Morrow, H Fukui, H Fukui, H Kenward, H Kenward, Hannah Kenward, JA Gylys, JA Rudd, Jonathan Elliott, K Olsson, Ludovic Pelligand, LX Cubeddu, M Marty, M Mutoh, N Percie du Sert, N Percie du Sert, PH Mulder De, PJ Hesketh, PJ Hesketh, PL Andrews, RJ Gralla, RM Stern, RM Stern, S Kretzing, S Poli-Bigelli, SG Allan, SP Chawla, Terry Lee, TM Hyde, V Napadow, VA Puente-Redondo de la   +47 more
core   +2 more sources

Randomised, placebo‐controlled trial and meta‐analysis show benefit of ondansetron for irritable bowel syndrome with diarrhoea: The TRITON trial

Alimentary Pharmacology and Therapeutics, 2023
Ondansetron may be beneficial in irritable bowel syndrome with diarrhoea (IBS‐D).
D. Gunn, Rabia Topan, Lorna Barnard, R. Fried, I. Holloway, Richard Brindle, M. Corsetti, M. Scott, A. Farmer, K. Kapur, David S Sanders, M. Eugenicos, Nigel Trudgill, P. Whorwell, J. Mclaughlin, A. Akbar, L. Houghton, P. G. Dinning, Qasim Aziz, A. Ford, A. Farrin, R. Spiller   +21 more
semanticscholar   +1 more source

Acupuncture combined with ondansetron for prevention of postoperative nausea and vomiting in high‐risk patients undergoing laparoscopic gynaecological surgery: A randomised controlled trial

United European Gastroenterology journal, 2023
Background Consensus guidelines recommend the use of multiple antiemetics as prophylaxis in patients at high risk of postoperative nausea and vomiting (PONV), but the evidence regarding combining acupuncture and antiemetics as a multimodal approach was ...
Shi-Yan Yan, Mingjun Xu, X. Zou, Zhiyi Xiong, Hewen Li, Jingwen Yang, W. Cao, Ziqiong Zhu, Cunzhi Liu   +8 more
semanticscholar   +1 more source

Ondansetron-induced QT prolongation among various age groups: a systematic review and meta-analysis

Egyptian Heart Journal, 2023
Ondansetron is a selective 5-hydroxytryptamine type 3 serotonin-receptor antagonist with antiemetic properties used inadvertently in the emergency department for controlling nausea.
Kamaldeep Singh, Arpit Jain, Ishita Panchal, Hritik Madan, Anubhav Gupta, Aakanksha Sharma, Surabhi Gupta, A. Kostojchin, Anmol Singh, Ishanjit Singh Sandhu, Jayesh Mittal, L. Bhogal, S. Kolli, V. R. Bejugam, S. Chaturvedi, A. Bhalla, S. Piplani   +16 more
semanticscholar   +1 more source

Development of a Generic Physiologically‐Based Pharmacokinetic Model for Lactation and Prediction of Maternal and Infant Exposure to Ondansetron via Breast Milk

Clinical pharmacology and therapy, 2022
Ondansetron is commonly used in breastfeeding mothers to treat nausea and vomiting. There is limited information in humans regarding safety of ondansetron exposure to nursing infants and no adequate study looking at ondansetron pharmacokinetics during ...
Kathleen M. Job, A. Dallmann, S. Parry, G. Saade, D. Haas, B. Hughes, P. Berens, Jia-Yu Chen, Christina Fu, K. Humphrey, Christoph P. Hornik, Stephen Balevic, K. Zimmerman, K. Watt   +13 more
semanticscholar   +1 more source

Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort

JAMA Network Open, 2021
Key Points Question What is the association between ondansetron exposure during pregnancy and the risk of adverse fetal outcomes? Findings In this meta-analysis of cohort studies of 456 963 pregnancies in 3 countries, treatment with ondansetron was not ...
C. Dormuth, B. Winquist, Anat Fisher, Fangyun Wu, P. Reynier, S. Suissa, Matthew Dahl, Zhihai Ma, Xinya Lu, Jianguo Zhang, C. Raymond, K. Filion, R. Platt, C. Moriello, J. Paterson   +14 more
semanticscholar   +1 more source

Advancing non-sterile pediatric pharmacotherapy through automated compounding and 3D printing of ondansetron hcl dihydrate dosage forms. [PDF]

J Oncol Pharm Pract
Bahman M, Bernhardt MB, Brasher CA, Lahtinen J, Airaksinen S, Topelius NS.   +5 more
europepmc   +2 more sources

Oral ondansetron for paediatric gastroenteritis in primary care: a randomised controlled trial

The British journal of general practice : the journal of the Royal College of General Practitioners, 2021
Background Acute gastroenteritis (AGE) affects almost all children aged ≤5 years. In secondary care, ondansetron was found to be effective at reducing vomiting. Aim To determine the effectiveness of adding oral ondansetron to care as usual (CAU) to treat
Irma J. Bonvanie, A. Weghorst, G. Holtman, Heleen A Russchen, Freek Fickweiler, H. Verkade, B. Kollen, M. Berger   +7 more
semanticscholar   +1 more source

Selective Laser Sintering 3D Printing of Orally Disintegrating Printlets Containing Ondansetron

Pharmaceutics, 2020
The aim of this work was to explore the feasibility of using selective laser sintering (SLS) 3D printing (3DP) to fabricate orodispersable printlets (ODPs) containing ondansetron.
Nour Allahham, Fabrizio Fina, Carmen Marcuta, Lilia Kraschew, W. Mohr, S. Gaisford, A. Basit, A. Goyanes   +7 more
semanticscholar   +1 more source

Bimodal release ondansetron for acute gastroenteritis among adolescents and adults: A randomized clinical trial [PDF]

, 2019
Importance: Vomiting resulting from acute gastroenteritis is commonly treated with intravenous antiemetics in acute care settings. If oral treatment were beneficial, patients might not need intravenous administered hydration or medication. Furthermore, a
Avarello, Jahn, Fathi, Reza, Hahn, Barry, House, Stacey L, Kalfus, Ira N, Lovato, Luis M, Meltzer, Andrew C, Miller, Joseph B, Plasse, Terry F, Raday, Gilead, Silverman, Robert A, Yan, Eric C   +11 more
core   +2 more sources