Results 1 to 10 of about 39,707 (313)

Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study [PDF]

BMC Veterinary Research, 2017
Nausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to determine the efficacy of three classes of antiemetic drugs in a novel low dose cisplatin model of nausea and vomiting and measure change
A Freeman, A Tidholm, AM Holmes, B Otto, C Pirri, C Rojas, CC Horn, CC Horn, CJ Henry, DB Smith, DB Zamble, DG Warr, F Roila, F Roila, FD Tattersall, GJ Sanger, GJ Sanger, GR Morrow, H Fukui, H Fukui, H Kenward, H Kenward, Hannah Kenward, JA Gylys, JA Rudd, Jonathan Elliott, K Olsson, Ludovic Pelligand, LX Cubeddu, M Marty, M Mutoh, N Percie du Sert, N Percie du Sert, PH Mulder De, PJ Hesketh, PJ Hesketh, PL Andrews, RJ Gralla, RM Stern, RM Stern, S Kretzing, S Poli-Bigelli, SG Allan, SP Chawla, Terry Lee, TM Hyde, V Napadow, VA Puente-Redondo de la   +47 more
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Association between early ondansetron use and the risk of sepsis in intensive care unit patients: a secondary data of the Medical Information Mart for Intensive Care IV database. [PDF]

BMJ Open
Objective This study planned to analyse the association between ondansetron use within 24 hours before intensive care unit (ICU) admission to within 48 hours after ICU admission and the risk of sepsis in ICU patients.Design A cohort study.Setting and ...
Liu X, Liu E, Kou Q.
europepmc   +2 more sources

Comparison of aprepitant versus ondansetron for prevention of postoperative nausea and vomiting: A systematic review and meta-analysis with trial sequential analysis. [PDF]

Indian J Anaesth
Background and Aims: Postoperative nausea and vomiting (PONV) is a common complication after surgery. Preventing PONV in high-risk patients often requires a multimodal approach combining antiemetic drugs with diverse mechanisms.
Singh MP, Gurunthalingam MP, Gupta A, Singh J.   +3 more
europepmc   +2 more sources

The Effect of Maropitant, Ondansetron and Metoclopramide on Dexmedetomidine-Induced Vomiting in Cats. [PDF]

Vet Med Sci
ABSTRACT Objectives Vomiting is frequently observed in cats after dexmedetomidine administration. This study aimed to compare the efficacy of different antiemetics in preventing vomiting in cats after dexmedetomidine administration. Methods Sixty‐four cats were randomly allocated to receive saline solution (0.9% NaCl, 0.1 mL/kg, SC), maropitant (1 mg ...
Gölgeli Bedir A, Yanmaz LE, Okur S, Şenocak MG, Turgut F, Kocaman Y, Orhun ÖT, Ersöz U, Baykal B.   +8 more
europepmc   +2 more sources

Antiemetic use among pregnant women in the United States: the escalating use of ondansetron [PDF]

Pharmacoepidemiology and Drug Safety, 2017
PURPOSE: To examine ondansetron use in pregnancy in the context of other antiemetic use among a large insured United States population of women delivering live births.
Andrade, Susan E., Bird, Steven T., Greene, Patty, Haffenreffer, Katherine, Reichman, Marsha, Sahin, Leyla, Tassinari, Melissa S., Taylor, Lockwood G., Toh, Sengwee   +8 more
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The association between ondansetron use and mortality risk of traumatic brain injury patients: a population-based study. [PDF]

Front Pharmacol
Background:Traumatic brain injury (TBI) patients suffer high risks of mortality. Ondansetron has been verified to be effective in improving the prognosis of some kinds of critically ill patients. We design this study to explore whether ondansetron use is
Wang R, Zhang J, Xu J, He M.
europepmc   +2 more sources

Comparison of Ondansetron versus Clonidine efficacy for prevention of postoperative pain, nausea and vomiting after orthognathic surgeries : a triple blind randomized controlled trial [PDF]

Medicina Oral, 2018
The aim of this randomized controlled triple blind trial was to compare the efficacy of clonidine with dexamethasone versus ondansetron with dexamethasone for postoperative pain, nausea and vomiting prevention in orthognathic surgery patients.
Eshghpour, Majid, Hashemipour, Maryam Alsadat, Hosseini-Abrishami, Majid, Mianbandi, Vajiheh, Samieirad, Sahand, Shadkam, Elaheh, Sharifian-Attar, Alireza   +6 more
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Prophylactic ondansetron for preventing intraoperative shivering, nausea and vomiting during spinal anesthesia for cesarean section: a randomized controlled trial. [PDF]

Front Pharmacol
BackgroundShivering, nausea and vomiting are common complications in cesarean section during neuraxial anesthesia. The aim of this study was to investigate the effects of prophylactic use of ondansetron on intraoperative shivering, nausea and vomiting in
Zhang Y, Xia F, Zhang W, Lv A.
europepmc   +2 more sources

Clinical Impact of Specific Extraocular Muscle Manipulation and the Oculocardiac Reflex on Postoperative Vomiting in Pediatric Strabismus Surgery: A Multicenter, Observational Study. [PDF]

Paediatr Anaesth
ABSTRACT Background Strabismus surgery, which is commonly performed in children, poses a high risk of postoperative vomiting. The current anesthesia guidelines for the prevention of postoperative vomiting in children are based on heterogeneous populations involving different types of surgery, and risk factors for postoperative vomiting in, specifically,
Kojima T, Yamauchi Y, Fujiwara T, Obara S, Sueda A, Takahashi R, Yasuda S, Kitoh H.   +7 more
europepmc   +2 more sources

The therapeutic targets and signaling mechanisms of ondansetron in the treatment of critical illness in the ICU. [PDF]

Front Pharmacol
BackgroundThere is accumulating evidence regarding the benefits of the 5-HT3 receptor antagonist ondansetron for the treatment of critical illness due to its potential anti-inflammatory effect.
Tao L, Zhang Z, Li C, Huang M, Chang P.
europepmc   +2 more sources