Reconsidering Ondansetron for Smoking Cessation: A Call for Renewed Investigation. [PDF]
Pharmacology Research &Perspectives, Volume 13, Issue 6, December 2025.
Tam A, Munsar Z, Opler DJ.
europepmc +2 more sources
Clinical Characteristics and Outcomes of Rome IV Diarrhea-Predominant Irritable Bowel Syndrome and Functional Diarrhea Prescribed With Ondansetron: A Real-World Study. [PDF]
In a cohort of 92 patients with chronic diarrhea (irritable bowel syndrome diarrhea predominant and functional diarrhea), nearly 74% of patients reported an improvement in their symptoms with ondansetron. Symptom relief was maintained long‐term with a low‐dose therapy.
Sbarigia C +5 more
europepmc +2 more sources
Association Between Discharge Medications and Oncologic Post-Embolization-Syndrome-Related Outcomes. [PDF]
ABSTRACT Background Post‐embolization syndrome after transarterial chemoembolization (TACE) and Yttrium‐90 radioembolization (TARE) causes significant morbidity. Understanding whether discharge prescriptions influence short‐term outcomes may guide standardized pain‐management strategies.
Li H +10 more
europepmc +2 more sources
High-Throughput Screening Using the Self-Controlled Tree-Based Scan Statistic to Identify Medications Associated With Hospitalization for Severe Acute Liver Injury. [PDF]
ABSTRACT Background Medications associated with acute liver injury (ALI) are primarily identified by case reports. High‐throughput screening of real‐world data could be leveraged to detect hepatotoxicity signals. Objective To apply tree‐based scan statistics in real‐world data to identify drugs associated with hospitalization for severe ALI among ...
Lo Re V +5 more
europepmc +2 more sources
Purpose: This study was conducted to test whether blocking the serotonin receptors by intravenous [IV] ondansetron; can help in reducing the hypotensive bradycardic events [HB events] associated with shoulder arthroscopy done in the sitting position ...
Riham Hasanein, Wael El-Sayed
doaj +1 more source
Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy. [PDF]
Our study shows that in Indonesian cancer patients treated with highly cytostatic emetogenic, carriership of the CTG haplotype of the ABCB1 gene is related to an increased risk of delayed chemotherapy-induced nausea and ...
Baak-Pablo, Renee F +8 more
core +2 more sources
Background: The purpose of the present study was to evaluate the efficacy of midazolam-ondansetron combination in prevention of postoperative nausea and vomiting (PONV) after middle ear surgery and its comparison with using midazolam or ondansetron alone.
Azim Honarmand +2 more
doaj +3 more sources
Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT3 receptor antagonists [PDF]
PURPOSE: The ferret cisplatin emesis model has been used for ~30 years and enabled identification of clinically used anti-emetics. We provide an objective assessment of this model including efficacy of 5-HT(3) receptor antagonists to assess its ...
A Fink-Jensen +153 more
core +2 more sources
Background In mildly to moderately dehydrated patients with acute gastroenteritis (AGE), oral rehydration therapy (ORT) is the treatment of choice. Though ondansetron is a very effective antiemetics and leads to succeed ORT, there have been reports QT ...
Heewon Yang +4 more
doaj +1 more source
Background: Hyperemesis gravidarum is a serious pregnancy complication that affects approximately 1% of pregnancies worldwide.Objective: To determine whether the use of ondansetron during pregnancy is associated with abnormal pregnancy outcomes.Search ...
Xiao Cao +8 more
doaj +1 more source

