Ondansetron Exposure Changes in a Pregnant Woman [PDF]
Pregnancy results in many physiologic changes that can alter the pharmacokinetic profiles of medications used during pregnancy. One of the primary factors leading to these pharmacokinetic changes is altered activity of drug-metabolizing enzymes ...
Caritis, Steve N.+6 more
core +1 more source
The role of ondansetron in the management of cholestatic or uremic pruritis - a systematic review [PDF]
Pruritus associated with hepatic or renal failure can be a troublesome symptom, refractory to treatment, associated with significant physical and emotional distress, and reduction in quality of life for patients already burdened with chronic disease ...
Clark, Katherine+4 more
core +1 more source
Comparison of ondansetron with ondansetron and dexamethasone in prevention of PONV in diagnostic laparoscopy [PDF]
To compare the efficacy of ondansetron-dexamethasone combination with ondansetron alone for prevention of postoperative nausea and vomiting (PONV).This double blind, randomized study was carried out in 51 female patients, aged 20-40 yr, ASA-1 physical status undergoing gynecological diagnostic laparoscopy. Group 1 (n = 26) received 4 mg ondansetron i.v.
Yatindra Kumar Batra+3 more
openaire +2 more sources
Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) [PDF]
The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
Adamek+196 more
core +1 more source
Ondansetron in Multiple Sclerosis [PDF]
Two young women with chronic nausea and vertigo caused by multiple sclerosis responded to the introduction and maintenance of the 5HT3 receptor antagonist, ondansetron. Palliative care is a neglected aspect of management of degenerative neurological diseases and these cases highlight the approaches that may be used to manage difficult symptoms in the ...
openaire +3 more sources
Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study [PDF]
Nausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to determine the efficacy of three classes of antiemetic drugs in a novel low dose cisplatin model of nausea and vomiting and measure change
A Freeman+47 more
core +1 more source
Economic evaluation of ondansetron: Preliminary analysis using clinical trial data prior to price setting [PDF]
This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright © 1992 Macmillan Press Ltd.This study combines secondary analysis of efficacy and side-effect data from a randomised ...
Buxton, MJ, O'Brien, BJ
core +1 more source
Effects of Modification of Pain Protocol on Incidence of Post Operative Nausea and Vomiting. [PDF]
BackgroundA Perioperative Surgical Home (PSH) care model applies a standardized multidisciplinary approach to patient care using evidence-based medicine to modify and improve protocols.
Ahn, Kyle+7 more
core +2 more sources
Ondansetron compared with ondansetron plus metoclopramide in the prevention of cisplatin-induced emesis [PDF]
To determine the contribution of metoclopramide to the efficacy of ondansetron in control of cisplatin-induced emesis, ondansetron was compared with ondansetron plus metoclopramide for antiemetic efficacy in a randomized double-blind trial. Enrolled 66 patients were treated with cisplatin(60mg/m2) in combination with etoposide, flourouracil, or ...
Cheol Whan Lee+6 more
openaire +3 more sources
Interventions for treating hyperemesis gravidarum. [PDF]
BACKGROUND: Hyperemesis gravidarum is a severe form of nausea and vomiting in pregnancy affecting 0.3% to 1.0% of pregnancies, and is one of the most common indications for hospitalization during pregnancy.
Abas+96 more
core +2 more sources