Results 41 to 50 of about 16,776 (152)

Comparison of aprepitant versus ondansetron for prevention of postoperative nausea and vomiting: A systematic review and meta-analysis with trial sequential analysis

Indian Journal of Anaesthesia
Background and Aims: Postoperative nausea and vomiting (PONV) is a common complication after surgery. Preventing PONV in high-risk patients often requires a multimodal approach combining antiemetic drugs with diverse mechanisms.
Madhusudan P. Singh, Meenalotchini P. Gurunthalingam, Ayushee Gupta, Juhi Singh   +3 more
doaj   +1 more source

Ondansetron-induced QT prolongation among various age groups: a systematic review and meta-analysis

The Egyptian Heart Journal, 2023
Background Ondansetron is a selective 5-hydroxytryptamine type 3 serotonin-receptor antagonist with antiemetic properties used inadvertently in the emergency department for controlling nausea.
Kamaldeep Singh, Arpit Jain, Ishita Panchal, Hritik Madan, Anubhav Gupta, Aakanksha Sharma, Surabhi Gupta, Anastas Kostojchin, Anmol Singh, Ishanjit Singh Sandhu, Jayesh Mittal, Loveleen Bhogal, Shiny Teja Kolli, Vishal Reddy Bejugam, Salil Chaturvedi, Akhil Bhalla, Shobhit Piplani   +16 more
doaj   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Ondansetron in dogs with nausea associated with vestibular disease: A double‐blinded, randomized placebo‐controlled crossover study

Journal of Veterinary Internal Medicine, 2022
Background Nausea and emesis can be, among other signs, common manifestations of acute vestibular system dysfunction in dogs. Currently, antiemetic drugs, such as maropitant and metoclopramide, are used commonly, but do not appear to control nausea.
Lea Henze, Sarah Foth, Sebastian Meller, Friederike Twele, Marios Charalambous, Hannah Kenward, Jonathan Elliott, Ludovic Pelligand, Holger A. Volk   +8 more
doaj   +1 more source

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

Addiction, EarlyView.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source

Anti-dyskinetic efficacy of 5-HT3 receptor antagonist in the hemi-parkinsonian rat model

IBRO Reports, 2019
Parkinson's disease is a progressive debilitative neurodegenerative disease characterised mostly with bradykinesia, tremor, catatonia, drooping posture, unsteady gate and unstable steps.
Nazanin Aboulghasemi, Mahsa Hadipour Jahromy, Amir Ghasemi   +2 more
doaj   +1 more source

Cost‐effectiveness of a transition from volatile anaesthesia to total intravenous anaesthesia to reduce carbon footprint: an economic modelling study

Anaesthesia, EarlyView.
Summary Introduction The UK NHS is committed to reaching net zero carbon emissions by 2040. Volatile anaesthetic agents are potent greenhouse gases and alternative intravenous methods exist. We aimed to predict the cost‐effectiveness of a transition from volatile anaesthesia to total intravenous anaesthesia to reduce carbon emissions. Methods A general
Daniel Leslie, Christopher J. Mullington
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Comparison Study of Preemptive Effect of Intratechal Fentanyl with Intravenous Ondansetron, Dexamethasone, and Dexamethasone plus Ondansetron on Shivering during Surgeries under Spinal Anesthesia with Bupivacaine

مجله دانشکده پزشکی اصفهان, 2017
Background: Previous studies showed that dexamethasone and ondansetron had effect on preventing shivering in surgeries under spinal anesthesia but comparison of the two drugs was not studied.
Mohammadreza Safavi, Azim Honarmand, Mina Barzegar   +2 more
doaj  

The Effect of Intramuscular Onusetron Treatment on Prognosis in Patients Diagnosed with Acute Gastroenteritis

Journal of Pediatric Emergency and Intensive Care Medicine, 2023
Introduction:Vomiting is an important symptom that limits oral intake and may result in hospitalizations and prolonged hospital stays for intravenous fluid therapy.
İlknur Bodur, Betül Öztürk, Aytaç Göktuğ, Raziye Merve Yaradılmış, Muhammed Mustafa Güneylioğlu, Ali Güngör, Can Demir Karacan, Nilden Tuygun   +7 more
doaj   +1 more source