Results 131 to 140 of about 18,724 (299)

Study on the Rheological Properties and Constitutive Model of Shenzhen Mucky Soft Soil

open access: yes, 2014
In order to obtain the basic parameters of numerical analysis about the time-space effect of the deformation occurring in Shenzhen deep soft-soil foundation pit, a series of triaxial consolidated-undrained shear rheology tests on the peripheral mucky ...
Zhao, Bao-yun   +4 more
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A Inibição da síntese proteica no hipocampo dorsal de ratos impede a tolerância ao midazolam induzida pela experiência prévia no labirinto em cruz elevado [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011A tolerância ao efeito do tipo ansiolítico de drogas pode se desenvolver como resultado de uma ...
Gazarini, Lucas
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Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

A novel CFD-DEM coupling method with moving boundary for simulating one-dimensional consolidation test

open access: yesIOP Conference Series: Earth and Environmental Science
Abstract The conventional CFD-DEM coupling method fails to dynamically modify the position of the drainage boundary during the simulation of one-dimensional consolidation tests (1d CT), resulting in inaccuracies in the numerical results.
J H He, M G Li, J J Chen, X Xiao
openaire   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

"Effects of a bank consolidation promotion policy: Evaluating Bank Law in 1927 Japan" [PDF]

open access: yes
This paper investigates the impact of bank consolidations promoted by government policy, using data from pre-war Japan when the Ministry of Finance promoted bank consolidations by dint of the Bank Law of 1927.
Michiru Sawada, Tetsuji Okazaki
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

Ground compaction due to vibrodriving of piles [PDF]

open access: yes, 1996
Civil engineering construction frequently requires the use of piles to carry structural loads to stronger ground strata or to control lateral ground movements. A variety of techniques are available to install piles into the ground. Of central interest to
Bement, R.A.P., Bement, R
core  

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